Protein Alignment Hsp60C and Cct6a

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001028856.1
• Gene: Cct6a / 288620
• RGDID: 1304763
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 571
• Identity: 123/571 - (21%)
• Similarity: 227/571 - (39%)
• Gaps: 93/571 - (16%)

  Fly    37 RAMMLQGVDV-----LADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKD-KFQNIGA 95
            ||.....|::     |.|.:...:||||...::....|..|:||||     ::.|.: :.|:..|
  Rat    15 RAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG-----NVLLHEMQIQHPTA 74

  Fly    96 KLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAIETVKDNLR--RL 158
            .|:..||...::..|||||:..::...:.|:....||.|..|..|..|...|.|.....|.  ::
  Rat    75 SLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEQVKV 139

  Fly   159 SRPVNTPEEICQVA--TISANGDKSVGNLISEAIKKVGRDGVITVKDGKTLCD------------ 209
            |:.::. |.:..||  ::.......:.::::||:.    |.::.::......|
  Rat   140 SKEMDR-ETLIDVARTSLRTKVHAELADVLTEAVV----DSILAIRKKDEPIDLFMVEIMEMKHK 199

  Fly   210 ---ELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIK-SAPSIVPALELANAQRKP 270
               :..:|.|:..|.|...|       ..|...::|.:|.|...:: ....:.......:|:.:.
  Rat   200 SETDTSLIRGLVLDHGARHP-------DMKKRVENAYILTCNVSLEYEKTEVNSGFFYKSAEERE 257

  Fly   271 LVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENL----MDMAVATGGIVFGDEANM 331
            .::.||....|.....:|...|   :||.....||....::.:    :| |:|..|||....|..
  Rat   258 KLVKAERKFIEDRVKKIVELKK---KVCGDSDKGFVVINQKGIDPFSLD-ALAKEGIVALRRAKR 318

  Fly   332 VRLEDIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEKRVEGLREAIKESTSSYEKEKMQERLAR 396
            ..:|.:.::    .|.:.::..|           ::.....|....:.|.|...||....|:...
  Rat   319 RNMERLTLA----CGGIALNSFD-----------DLNPDCLGHAGLVYEYTLGEEKFTFIEKCNN 368

  Fly   397 LSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVEEG-IVPGGG---TALLRCIQKLN-DLKG 456
            ..| |.|| |.|.:...:::.||.:.|.|.|.:.|:::| :|||.|   .||...:.|.. .:||
  Rat   369 PRS-VTLL-VKGPNKHTLTQIKDAIRDGLRAVKNAIDDGCVVPGAGAVEVALAEALIKYKPSVKG 431

  Fly   457 ANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKVEILDGD----YGYDALKGEYGNMIERG 517
            ..:   :|::....||.:....:|:|:|.|....:.||:....:    .|.|...||.....|.|
  Rat   432 RAQ---LGVQAFADALLIIPKVLAQNSGFDLQETLVKVQAEHSESGQLVGVDLNTGEPMVAAEMG 493

  Fly   518 IIDPTKVVRTAISDAAGVASLLTTAEAVVTELPLEEAAAAGAAAGLGALGG 568
            :.|...|.:..:.....:|:.:...:.::             .||:.:|.|
  Rat   494 VWDNYCVKKQLLHSCTVIATNILLVDEIM-------------RAGMSSLKG 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	119/549 (22%)
Cct6a	NP_001028856.1	chap_CCT_zeta	3..530	CDD:274088	121/568 (21%)