Protein Alignment Hsp60C and Hspd1

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_034607.3
• Gene: Hspd1 / 15510
• MGIID: 96242
• Length: 573
• Species: Mus musculus
• Alignment Length: 575
• Identity: 414/575 - (72%)
• Similarity: 483/575 - (84%)
• Gaps: 9/575 - (1%)

  Fly     4 MFRYTNTLQRTAKISHVL---WARNYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIE 65
            |.|....|::...:|..|   ..|.|||||:||.:.||:||||||:||||||||||||||.||||
Mouse     1 MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIE 65

  Fly    66 QSWGSPKITKDGVTVAKSIALKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEK 130
            |||||||:|||||||||||.||||::||||||||||||||||||||||||||||||:||||||||
Mouse    66 QSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEK 130

  Fly   131 ISRGASPVEIRRGVMLAIETVKDNLRRLSRPVNTPEEICQVATISANGDKSVGNLISEAIKKVGR 195
            ||:||:|||||||||||::.|...|::.|:||.|||||.|||||||||||.:||:||:|:|||||
Mouse   131 ISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGR 195

  Fly   196 DGVITVKDGKTLCDELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPA 260
            .|||||||||||.||||:|||||||||||||||||||||.|.|||||.:|..||||.|..|||||
Mouse   196 KGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPA 260

  Fly   261 LELANAQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMAVATGGIVF 325
            ||:|||.||||||||||::.|||||||:|||||||||.||||||||||||..|.|||:||||.||
Mouse   261 LEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVF 325

  Fly   326 GDEANMVRLEDIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEKRVEGLREAIKESTSSYEKEKM 390
            |:|...:.|||::..|.|:||||:|:|||.|||||||.||.:|||::.:.|.:..:||.|||||:
Mouse   326 GEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKL 390

  Fly   391 QERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVEEGIVPGGGTALLRCIQKLNDLK 455
            .||||:||.|||:|:|||:|||||:||||||.|||||||||||||||.|||.||||||..|:.||
Mouse   391 NERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLK 455

  Fly   456 GANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKVEILDGDYGYDALKGEYGNMIERGIID 520
            .|||||.:|||||:|||::|.:||||||||:|:::|.|:.....:.||||:.|::.||:|:||||
Mouse   456 PANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIID 520

  Fly   521 PTKVVRTAISDAAGVASLLTTAEAVVTELPLEEAAAAGAAAGLGALGGMGMGGMG 575
            ||||||||:.||||||||||||||||||:|.||     ...|:||:|||| ||||
Mouse   521 PTKVVRTALLDAAGVASLLTTAEAVVTEIPKEE-----KDPGMGAMGGMG-GGMG 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	390/519 (75%)
Hspd1	NP_034607.3	GroEL	28..548	CDD:239460	390/519 (75%)