Protein Alignment Hsp60C and CCT6

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_311767.4
• Gene: CCT6 / 1272849
• VectorBaseID: AGAMI1_006633
• Length: 531
• Species: Anopheles gambiae
• Alignment Length: 584
• Identity: 118/584 - (20%)
• Similarity: 228/584 - (39%)
• Gaps: 129/584 - (22%)

  Fly    37 RAMMLQGVDVLA-----DAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAK 96
            ||.....:::.|     |.:...:||||...::....|..||||||..:...:.:|    :..|.
Mosquito    15 RAAQALAINITAAKGIQDVMKTNLGPKGTMKMLVSGAGDIKITKDGNVLLHEMQIK----HPTAS 75

  Fly    97 LVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAIETVKDNLRRLSRP 161
            |:...:...::..|||||:..::...:.|:....|:.|..|..|..|...|.....|.|.:::.|
Mosquito    76 LIARASTAQDDVTGDGTTSIVLIIGELLKQADLYIADGLHPRIIADGFDQARLQALDILEQIAHP 140

  Fly   162 VN-TPEEICQVATISANGDKSVGNLISEAIKKVGRDGVITVK-DGKTL--------------CDE 210
            :. ..|.:..:|..|..  ..|...:::.:..|..|.|:.:: :||.:              ..:
Mosquito   141 IEVNRENLLNIARTSLR--TKVHPDLADLLTDVCVDAVLAIRTEGKPVDLHMVELMEMQHKSATD 203

  Fly   211 LEVIEGMKFDRG-------------YI---------------SPYFINTSKGAKVEFQDALLLFC 247
            .::::|:..|.|             ||               |.:|..|:: .:.:|..|...|.
Mosquito   204 TQLVKGIVMDHGARHPDMPKRVENAYILTCNVSMEYEKSEVNSGFFYKTAE-EREKFVLAEREFI 267

  Fly   248 EKKIKSAPSIVPALELANAQRKPLVII-AEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKE 311
            |.::|..  |....::.:...|..|:| .:.::..:|..|.    |.|: |...:|      ::.
Mosquito   268 EDRVKKV--IELKRKVCDGTDKTFVVINQKGIDPMSLDMLA----KEGI-VALRRA------KRR 319

  Fly   312 NLMDMAVATGGIVFGDEANMVRLEDIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEKRVEGLRE 376
            |:..:|:|.||:......||                     |::.|    |...:|.:.|.|
Mosquito   320 NMERLALACGGMAMNSFDNM---------------------DESCL----GFAGQVYEHVLG--- 356

  Fly   377 AIKESTSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVEE-GIVPGG 440
               |:..::.::      .:....|.:|..|.:... :::.||.:.|.|.:...|||: .:|||.
Mosquito   357 ---ENKYTFVED------CKNPLSVTILMKGPNKHT-LAQIKDAIRDGLRSINNAVEDKKLVPGA 411

  Fly   441 GTALLRCIQKLND----LKGANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKVE----IL 497
            |...:|...||.:    :||..   .:.|:....|:.:....:|.|:|.|....:.:::    :.
Mosquito   412 GAFEVRVHNKLREYAKTVKGKT---RLAIQAYADAMLVVPKILAVNSGYDAQDTIVRLQEEGLLN 473

  Fly   498 DGDYGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAVVTELPLEEAAAAGAAA 561
            :...|.|...||....::.||.|...|.:..::.:..:|         |..|.::|...||.::
Mosquito   474 EEPIGLDLSTGEPMKPVDLGIFDNYIVKKQILNSSTIIA---------VNILLVDEIMRAGMSS 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	114/569 (20%)
CCT6	XP_311767.4	TCP1_zeta	7..526	CDD:239458	117/580 (20%)