DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-theta and Igsf9

DIOPT Version :9

Sequence 1:NP_723103.1 Gene:DIP-theta / 33795 FlyBaseID:FBgn0051646 Length:606 Species:Drosophila melanogaster
Sequence 2:NP_001139272.1 Gene:Igsf9 / 93842 MGIID:2135283 Length:1179 Species:Mus musculus


Alignment Length:340 Identity:84/340 - (24%)
Similarity:139/340 - (40%) Gaps:51/340 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   197 LRIRDVKESDKGWYMCQI--------NTDPMKSQVGYLDVVVPPDILDYPTSTDMVIREGSNVTL 253
            |:|..::..|:|||.|::        ..|.......:|.|..||...:.|... :.::|...|||
Mouse    93 LQIEGLRVEDQGWYECRV
LFLDQHSPEQDFANGSWVHLTVNSPPQFQETPPLV-LEVKELEAVTL 156

  Fly   254 KCAATGSPTPTITWRREGGELIPLPNGAEAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSK 318
            :|.|.|||.|.:||:..|.:   |..|...|......|.|.:|.|.:.|.|.|.||:. ..:::.
Mouse   157 RCVARGSPQPYVTWKFRGQD---LGKGQGQVQVQNGTLWIRRVERGSAGDYTCQASSS-EGSITH 217

  Fly   319 RVMLIVHFPPMIWI--QNQLVGAALTQNITLECQSEAYPKSINY-WMKNDTIIVPGERFVPETFE 380
            ...|:|..||:|.:  .|..|.:  :|:::|.|::||||.::.| |.::...:     |.....:
Mouse   218 ATQLLV
LGPPVIVVPPSNSTVNS--SQDVSLACRAEAYPANLTYSWFQDGVNV-----FHISRLQ 275

  Fly   381 SGYKITM--RLTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTTMTTMAPTVSINT---- 439
            |..:|.:  .|.:......|.|.|.||..|.......|.....:.....:|.|.|...:.|    
Mouse   276 SRVRILVDGSLWLQATQPDDAGHYTCVPSNGFLHPPSASAYLTVLYPAQVTVMPPETPLPTGMRG 340

  Fly   440 ---------VPVVLVKYNKEQRYGSSQNSNTNP-YNFNP--------GNSQQNTKLQRGKSNSKG 486
                     .|::.|.:.|:   |.:...:..| ::..|        ||.....:......||.|
Mouse   341 VIRCPVRANPPLLFVTWTKD---GQALQLDKFPGWSLGPEGSLIIALGNENALGEYSCTPYNSLG 402

  Fly   487 SDQSPSGLNNVFVGA 501
            : ..||.:..|.:.|
Mouse   403 T-AGPSPVTQVLLKA 416

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-thetaNP_723103.1 Ig 137..230 CDD:299845 10/40 (25%)
IG_like 137..230 CDD:214653 10/40 (25%)
IG_like 240..324 CDD:214653 26/83 (31%)
IGc2 247..310 CDD:197706 24/62 (39%)
Ig 327..419 CDD:299845 25/96 (26%)
IG_like 343..420 CDD:214653 20/79 (25%)
Igsf9NP_001139272.1 IG_like 28..110 CDD:214653 7/16 (44%)
Ig 136..223 CDD:386229 28/91 (31%)
Ig_3 227..305 CDD:372822 22/84 (26%)
Ig 341..404 CDD:386229 11/66 (17%)
Ig 436..500 CDD:319273
FN3 508..599 CDD:238020
FN3 625..715 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 767..807
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 819..842
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 942..974
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1016..1079
PDZ-binding 1177..1179
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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