DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-theta and opcml

DIOPT Version :9

Sequence 1:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_001072487.1	Gene:	opcml / 779942	XenbaseID:	XB-GENE-5831850	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	340	Identity:	104/340 - (30%)
Similarity:	162/340 - (47%)	Gaps:	45/340 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 HIAHHLAEMQNK--DELLEDIREDTVVNAIP----EKDLPKFGELLQNVTVPVSREAVLQCVVDN 155
            |:.||:..|...  ..||.       :..:|    :...||   .:.||||.....|:|:|.|||
Frog     9 HLYHHVCWMFGAALTVLLS-------ITGVPVRSGDAGFPK---AMDNVTVRQGDSAILRCTVDN 63

  Fly   156 LQTYKIAWLRVDTQTILTIQNHVITKNHRMSITHAEKRAWILRIRDVKESDKGWYMCQINTD--P 218
            ..| ::|||  :..|||...|...:.:.|:.:....|..:.:.|::|...|:|.|.|.:.||  |
Frog    64 RVT-RVAWL--NRSTILYTGNDKWSIDPRVVLLANTKSQYSIEIQNVDIYDEGPYTCSVQTDNHP 125

  Fly   219 MKSQVGYLDVVVPPDILDYPTSTDMVIREGSNVTLKCAATGSPTPTITWRREGGELIPLPNGAEA 283
            ..|:| :|.|.|.|.||:  .|:|:.:.|||.|.|:|.|||.|.|.:|||...|:       :..
Frog   126 KTSRV-HLIVQVAPQILN--ISSDITVNEGSTVALRCLATGRPEPAVTWRHFTGK-------SHR 180

  Fly   284 VAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLE 348
            ...:..:|.|..:.|...|.|.|.|:|.:.....::|.:.|::||.| ...:..||:|.|...|.
Frog   181 FVSDDEYLEITGITRDQSGQYECSAANDVSAPDIRKVRVTVNYPPYI-SDTRNTGASLGQKGILR 244

  Fly   349 CQSEAYPKSINYWMKNDTIIVPGERFVPETFESGYKITMR-----LTIYEVDIQDFGAYRCVAKN 408
            |.:.|.|.:...|.:.:|.:..|        ..|.:|..:     ||.:.|..:|:|.|.|||.|
Frog   245 CSASAVPLAEFQWYREETRLANG--------LDGVRIENKDHMSILTFFNVSEKDYGNYTCVASN 301

  Fly   409 SLGDTDGAIKLYHIP 423
            .||:::.::.||..|
Frog   302 KLGNSNASVILYAGP 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	33/94 (35%)
		IG_like	137..230	CDD:214653	33/94 (35%)
		IG_like	240..324	CDD:214653	26/83 (31%)
		IGc2	247..310	CDD:197706	22/62 (35%)
		Ig	327..419	CDD:299845	28/96 (29%)
		IG_like	343..420	CDD:214653	22/81 (27%)
opcml	NP_001072487.1	Ig	46..134	CDD:325142	32/91 (35%)
		Ig_3	138..207	CDD:316449	27/77 (35%)
		ig	228..312	CDD:278476	25/91 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H55663
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060