DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-theta and igsf9bb

DIOPT Version :9

Sequence 1:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	352	Identity:	99/352 - (28%)
Similarity:	145/352 - (41%)	Gaps:	77/352 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 KDLPKFGELLQNVTVPVSREAVLQCVVD---NLQTYKIAWLRVDTQTILTIQNHVITKNHRMSIT 188
            ::.|:|      ||.......:|.|.|.   |.|.|.:.|.:........|       |.|....
Zfish    27 REEPQF------VTSRAGETVILGCDVVHPLNGQPYVVEWFKFGVPIPFFI-------NFRFYPP 78

  Fly   189 HAEK----RAWI-----LRIRDVKESDKGWYMC-------QINTDPMKSQVGYLDVVVPPDILDY 237
            |.:.    ||.:     |||..|:..|:|||.|       |.:|....|.| :|.|..||...|.
Zfish    79 HVDPEYAGRASLHGKSSLRIERVRSEDQGWYECKVLMLEQQYHTFHNGSWV-HLTVNAPPTFTDT 142

  Fly   238 PTSTDMVIREGSNVTLKCAATGSPTPTITWRREGGELIPLPNGAEAVAYNGSFLTIAKVNRLNMG 302
            |... :..:||.::||.|.|.|:|.|:::|.|||.   |:.:..:....:|| ||:..::|.:.|
Zfish   143 PPQY-VEAKEGGSITLSCTAFGNPKPSVSWLREGN---PVQDSTKYKVSDGS-LTLVSISREDRG 202

  Fly   303 AYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINY---W--- 361
            ||.|.|.:.....| ....|:|..||.|....:.:...::|:....||:||||.::.|   |
Zfish   203 AYTCRAYSEQGEAV-HTTRLLVQGPPFIVSPPENITVNISQDAFFTCQAEAYPGNLTYTWFWEED 266

  Fly   362 ---MKND-----TIIVPGERFVPETFESGYKITMRLTIYEVDIQDFGAYRCVAKNSLGDTDGAIK 418
               .|||     :|::.|.                |.|.:|..:|.|.|.|...||||....|
Zfish   267 NVFFKNDLKRRVSILIDGS----------------LIISQVKPEDAGKYTCSPSNSLGRPPSA-- 313

  Fly   419 LYHIPQTTTMTTMAPTVSINTVPVVLV 445
                  :..:|...|...||..||:.|
Zfish   314 ------SAYLTVHYPARVINMPPVIYV 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	30/111 (27%)
		IG_like	137..230	CDD:214653	30/111 (27%)
		IG_like	240..324	CDD:214653	26/83 (31%)
		IGc2	247..310	CDD:197706	24/62 (39%)
		Ig	327..419	CDD:299845	29/105 (28%)
		IG_like	343..420	CDD:214653	26/90 (29%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	26/95 (27%)
		Ig	41..113	CDD:143165	22/78 (28%)
		IG_like	144..223	CDD:214653	26/84 (31%)
		IGc2	151..208	CDD:197706	23/60 (38%)
		I-set	227..319	CDD:254352	28/115 (24%)
		Ig	<263..319	CDD:299845	18/79 (23%)
		Ig_2	326..414	CDD:290606	5/9 (56%)
		IG_like	329..403	CDD:214653	3/6 (50%)
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010