DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-theta and dscama

DIOPT Version :9

Sequence 1:NP_723103.1 Gene:DIP-theta / 33795 FlyBaseID:FBgn0051646 Length:606 Species:Drosophila melanogaster
Sequence 2:XP_021334866.1 Gene:dscama / 568643 ZFINID:ZDB-GENE-050310-7 Length:2025 Species:Danio rerio


Alignment Length:501 Identity:113/501 - (22%)
Similarity:193/501 - (38%) Gaps:94/501 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   136 LQNVTVPVSREAVLQCVVDNLQTYKIAWLRVDTQTILTIQNHVITKNHRMSITHAEKRAWILRIR 200
            ::|:|.....:..:.|.|.....|.|.|.:         .::::..|.|.   .|.:....|::.
Zfish   511 MKNLTAIAGWDMYIHCHVIGYPYYSIKWFK---------NSNLLPFNDRQ---RAFENNGTLKLL 563

  Fly   201 DV-KESDKGWYMCQINTDP--MKSQVGYLDVVVPPDI--LDYPTSTDMVIREGSNVTLKCAATGS 260
            :| ||.|:|.|.|.:...|  .|:|..::.|.|||.|  .::|..:     .|..|.:.|.....
Zfish   564 NVQKELDEGEYSCHVQVQPQLFKNQSVHVTVKVPPFIQPFEFPRYS-----IGHRVFVPCVVRSG 623

  Fly   261 PTP-TITWRREGGELIPLPNGAEAVAYNG----SFLTIAKVNRLNMGAYLCIASNGIPPTVSKRV 320
            ..| :|||.::|..:    |.:..|..:.    |.|.|:.:.|::.|.|.|||.|. ...|..:.
Zfish   624 DLPISITWEKDGKSI----NASLGVTIDNIDFTSSLRISNLQRVHNGTYTCIAQND-AAVVKYQS 683

  Fly   321 MLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINYWMKNDTIIVPGERFVPETFESGYKI 385
            .|||..||...:|.|.......:::.|.|.::..|:....|..:....||  :|.|....||:::
Zfish   684 QLIVRVPPRFKVQPQDQDGIYGKSVILNCSADGEPRPTIEWKYSKGAGVP--QFQPIALNSGFRV 746

  Fly   386 TM----RLTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTTMTTMAPTVSINT------- 439
            .:    .|.|..|..:|.|.|.|...|.:| .|.:..:|...:...|.|..|..|:.|       
Zfish   747 QLLGNGSLLIKHVLEEDAGYYLCKVSNDVG-ADVSKSMYLNVKIPAMITSYPNNSLATKGEKIEM 810

  Fly   440 ------VPVVLVKYNKEQRYGSSQNSNTNPYNFNPGNSQQNTKLQRGKSNSKGSDQSPSGLNNVF 498
                  ...::|::.||.. ...|:...||..:....:.:|.           .|:         
Zfish   811 SCKAHGEKPIMVRWEKEVE-KEKQSHMINPDMWRHTVTVKNV-----------GDE--------- 854

  Fly   499 VGATSSLWNSQDHHSSSSSSSSASSRGRDHHQQQHHQQQ-------QQNHGSDHGASYR----SD 552
            |.:|..::.:....|...|..:.:|.|.|....|...|:       :.....:...:.|    .|
Zfish   855 VVSTLQIYPTMREDSGFFSCHAINSYGEDRGILQLTVQEPPEPPKVEIREVKERTIALRWTMGFD 919

  Fly   553 GKSPHLTNHD--AKSLTDDLDRMQDLKGWASRLSPISPILGLSMIL 596
            |.| .:|.:|  .|:.|:..:|       |.|...:||.|..:.|:
Zfish   920 GNS-LITGYDIECKNKTETWER-------ARRTRDVSPTLNQATII 957

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-thetaNP_723103.1 Ig 137..230 CDD:299845 22/95 (23%)
IG_like 137..230 CDD:214653 22/95 (23%)
IG_like 240..324 CDD:214653 22/88 (25%)
IGc2 247..310 CDD:197706 19/67 (28%)
Ig 327..419 CDD:299845 24/95 (25%)
IG_like 343..420 CDD:214653 20/80 (25%)
dscamaXP_021334866.1 Ig 124..217 CDD:325142
I-set 236..311 CDD:254352
IG_like 321..402 CDD:214653
I-set 408..502 CDD:333254
IGc2 524..579 CDD:197706 16/66 (24%)
Ig 614..679 CDD:319273 19/69 (28%)
Ig_DSCAM 708..787 CDD:143211 21/81 (26%)
Ig 805..898 CDD:325142 17/113 (15%)
FN3 894..988 CDD:238020 15/72 (21%)
FN3 995..1092 CDD:238020
fn3 1100..1186 CDD:306538
fn3 1199..1282 CDD:306538
Ig 1312..1377 CDD:319273
fn3 1405..1471 CDD:306538
FN3 1492..1563 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.