DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-theta and igsf9ba

DIOPT Version :9

Sequence 1:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	348	Identity:	99/348 - (28%)
Similarity:	147/348 - (42%)	Gaps:	67/348 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 KDLPKFGELLQNVTVPVSREAVLQCVV----DNLQT-YKIAWLRVDTQTILTIQNHVITKNHRMS 186
            ::.|:|      ||.......||.|.|    :..|| |.:.|.:........|       |.|..
Zfish    27 REEPQF------VTARAGESVVLGCDVSHPLNGQQTPYVVEWFKFGVPIPFFI-------NFRFY 78

  Fly   187 ITHAEK----RAWI-----LRIRDVKESDKGWYMC-------QINTDPMKSQVGYLDVVVPPDIL 235
            ..|.:.    ||.:     |:|..|:..|:|||.|       |.:|....|.| :|.|..||...
Zfish    79 PPHVDPEYAGRASLHGKASLQIEQVRSEDQGWYECRVLMLEQQYDTFHNGSWV-HLTVNAPPTFS 142

  Fly   236 DYPTSTDMVIREGSNVTLKCAATGSPTPTITWRREGGELIPLPNGAEAVAYNGSFLTIAKVNRLN 300
            |.|... :..|||.::||.|.|.|:|.|.:||.|||.:   |.:..:....:|| ||:..:.|.:
Zfish   143 DTPPQY-VEAREGGSITLTCTAFGNPKPVVTWLREGDQ---LTSTRKYTVSDGS-LTVQAITRED 202

  Fly   301 MGAYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINY--WMK 363
            .|||.|.|.:.....: ....|:|..||.|....:.:...::||....||:||||.::.|  :.:
Zfish   203 RGAYSCRAHSDQGEAL-HTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWE 266

  Fly   364 NDTIIVPGERFVPETFESGYKITMR------LTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHI 422
            .|.:.          |::..|:.:|      |.||.|..:|.|.|.|...||||.:..|
Zfish   267 EDNVY----------FKNDLKLRVRIFIDGTLIIYRVKPEDAGKYTCSPSNSLGISPSA------ 315

  Fly   423 PQTTTMTTMAPTVSINTVPVVLV 445
              :..:|...|...:|..||:.|
Zfish   316 --SAYLTVQYPARVVNMPPVIYV 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	30/113 (27%)
		IG_like	137..230	CDD:214653	30/113 (27%)
		IG_like	240..324	CDD:214653	27/83 (33%)
		IGc2	247..310	CDD:197706	25/62 (40%)
		Ig	327..419	CDD:299845	29/99 (29%)
		IG_like	343..420	CDD:214653	26/84 (31%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652	26/97 (27%)
		I-set	139..225	CDD:254352	30/91 (33%)
		I-set	229..321	CDD:333254	28/109 (26%)
		Ig	345..415	CDD:325142
		Ig	438..503	CDD:319273
		FN3	511..606	CDD:238020
		FN3	622..706	CDD:238020
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810