DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-theta and Ntm

DIOPT Version :9

Sequence 1:NP_723103.1 Gene:DIP-theta / 33795 FlyBaseID:FBgn0051646 Length:606 Species:Drosophila melanogaster
Sequence 2:XP_017451354.1 Gene:Ntm / 50864 RGDID:620958 Length:367 Species:Rattus norvegicus


Alignment Length:309 Identity:103/309 - (33%)
Similarity:161/309 - (52%) Gaps:33/309 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   132 FGELLQNVTVPVSREAVLQCVVDNLQTYKIAWLRVDTQTILTIQNHVITKNHRMSITHAEKRAWI 196
            |.:.:.||||.....|.|:|.:||..| ::|||  :..|||...|.....:.|:.:....:..:.
  Rat    38 FPKAMDNVTVRQGESATLRCTIDNRVT-RVAWL--NRSTILYAGNDKWCLDPRVVLLSNTQTQYS 99

  Fly   197 LRIRDVKESDKGWYMCQINTD--PMKSQVGYLDVVVPPDILDYPTSTDMVIREGSNVTLKCAATG 259
            :.|::|...|:|.|.|.:.||  |..|:| :|.|.|.|.|::  .|:|:.|.||:|::|.|.|||
  Rat   100 IEIQNVDVYDEGPYTCSVQTDNHPKTSRV-HLIVQVSPKIVE--ISSDISINEGNNISLTCIATG 161

  Fly   260 SPTPTITWRREGGELIPLPNGAEAVAY--NGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVML 322
            .|.||:|||    .:.|     :||.:  ...:|.|..:.|...|.|.|.|||.:...|.:||.:
  Rat   162 RPEPTVTWR----HISP-----KAVGFVSEDEYLEIQGITREQSGEYECSASNDVAAPVVRRVKV 217

  Fly   323 IVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINYWMKNDTIIVPGERFVPETFESGYKI-- 385
            .|::||.| .:.:..|..:.|..||:|::.|.|.:...|.|:|..:|.|::        |.|:  
  Rat   218 TVNYPPYI-SEAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVEGKK--------GVKVEN 273

  Fly   386 ---TMRLTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTTMTTM 431
               ..|||.:.|...|:|.|.|||.|.||.|:.:|.|:.:.:.|:.|.:
  Rat   274 RPFLSRLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLL 322

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-thetaNP_723103.1 Ig 137..230 CDD:299845 31/94 (33%)
IG_like 137..230 CDD:214653 31/94 (33%)
IG_like 240..324 CDD:214653 32/85 (38%)
IGc2 247..310 CDD:197706 24/64 (38%)
Ig 327..419 CDD:299845 32/96 (33%)
IG_like 343..420 CDD:214653 28/81 (35%)
NtmXP_017451354.1 Ig 44..132 CDD:416386 30/91 (33%)
Ig strand A' 44..49 CDD:409353 4/4 (100%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 2/3 (67%)
FR2 64..70 CDD:409353 4/8 (50%)
Ig strand C 64..70 CDD:409353 4/8 (50%)
CDR2 71..83 CDD:409353 4/11 (36%)
Ig strand C' 72..76 CDD:409353 2/3 (67%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 7/33 (21%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 2/3 (67%)
Ig strand G 123..132 CDD:409353 4/9 (44%)
FR4 125..132 CDD:409353 3/7 (43%)
Ig_3 136..205 CDD:404760 29/79 (37%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand F 197..205 CDD:409353 4/7 (57%)
Ig 223..307 CDD:416386 30/92 (33%)
putative Ig strand A 223..229 CDD:409353 2/6 (33%)
Ig strand B 239..243 CDD:409353 2/3 (67%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 2/3 (67%)
Ig strand F 292..297 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 59 1.000 Domainoid score I10374
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4382
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8971
orthoMCL 1 0.900 - - OOG6_104123
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
109.870

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