Protein Alignment DIP-theta and NTM

DIOPT Version :9

• Sequence 1: NP_723103.1
• Gene: DIP-theta / 33795
• FlyBaseID: FBgn0051646
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001338930.1
• Gene: NTM / 50863
• HGNCID: 17941
• Length: 367
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 101/309 - (32%)
• Similarity: 160/309 - (51%)
• Gaps: 33/309 - (10%)

  Fly   132 FGELLQNVTVPVSREAVLQCVVDNLQTYKIAWLRVDTQTILTIQNHVITKNHRMSITHAEKRAWI 196
            |.:.:.||||.....|.|:|.:||..| ::|||  :..|||...|.....:.|:.:....:..:.
Human    38 FPKAMDNVTVRQGESATLRCTIDNRVT-RVAWL--NRSTILYAGNDKWCLDPRVVLLSNTQTQYS 99

  Fly   197 LRIRDVKESDKGWYMCQINTD--PMKSQVGYLDVVVPPDILDYPTSTDMVIREGSNVTLKCAATG 259
            :.|::|...|:|.|.|.:.||  |..|:| :|.|.|.|.|::  .|:|:.|.||:|::|.|.|||
Human   100 IEIQNVDVYDEGPYTCSVQTDNHPKTSRV-HLIVQVSPKIVE--ISSDISINEGNNISLTCIATG 161

  Fly   260 SPTPTITWRREGGELIPLPNGAEAVAY--NGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVML 322
            .|.||:|||    .:.|     :||.:  ...:|.|..:.|...|.|.|.|||.:...|.:||.:
Human   162 RPEPTVTWR----HISP-----KAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKV 217

  Fly   323 IVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINYWMKNDTIIVPGERFVPETFESGYKITM 387
            .|::||.| .:.:..|..:.|..||:|::.|.|.:...|.|:|..::.|::        |.|:..
Human   218 TVNYPPYI-SEAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKK--------GVKVEN 273

  Fly   388 R-----LTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTTMTTM 431
            |     |..:.|...|:|.|.|||.|.||.|:.:|.|:.:.:.|:.|.:
Human   274 RPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLL 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	31/94 (33%)
		IG_like	137..230	CDD:214653	31/94 (33%)
		IG_like	240..324	CDD:214653	32/85 (38%)
		IGc2	247..310	CDD:197706	24/64 (38%)
		Ig	327..419	CDD:299845	30/96 (31%)
		IG_like	343..420	CDD:214653	26/81 (32%)
NTM	NP_001338930.1	Ig	44..132	CDD:416386	30/91 (33%)
		Ig strand A'	44..49	CDD:409353	4/4 (100%)
		Ig strand B	51..59	CDD:409353	3/7 (43%)
		CDR1	59..63	CDD:409353	2/3 (67%)
		FR2	64..70	CDD:409353	4/8 (50%)
		Ig strand C	64..70	CDD:409353	4/8 (50%)
		CDR2	71..83	CDD:409353	4/11 (36%)
		Ig strand C'	72..76	CDD:409353	2/3 (67%)
		Ig strand C'	80..83	CDD:409353	0/2 (0%)
		FR3	84..118	CDD:409353	7/33 (21%)
		Ig strand D	87..94	CDD:409353	1/6 (17%)
		Ig strand E	97..103	CDD:409353	0/5 (0%)
		Ig strand F	110..118	CDD:409353	3/7 (43%)
		CDR3	119..123	CDD:409353	2/3 (67%)
		Ig strand G	123..132	CDD:409353	4/9 (44%)
		FR4	125..132	CDD:409353	3/7 (43%)
		Ig_3	136..205	CDD:404760	29/79 (37%)
		Ig strand A'	142..147	CDD:409353	2/4 (50%)
		Ig strand B	153..160	CDD:409353	2/6 (33%)
		Ig strand C	166..171	CDD:409353	4/8 (50%)
		Ig strand D	177..180	CDD:409353	1/2 (50%)
		Ig strand E	184..190	CDD:409353	2/5 (40%)
		Ig strand F	197..204	CDD:409353	3/6 (50%)
		Ig strand G	211..219	CDD:409353	3/7 (43%)
		Ig_3	222..299	CDD:404760	25/85 (29%)
		putative Ig strand A	223..229	CDD:409353	2/6 (33%)
		Ig strand B	239..243	CDD:409353	2/3 (67%)
		Ig strand C	252..256	CDD:409353	0/3 (0%)
		Ig strand E	278..282	CDD:409353	1/3 (33%)
		Ig strand F	292..297	CDD:409353	2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10656
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4481
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		mtm8497
orthoMCL	1	0.900	-	-		OOG6_104123
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3058
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.800