DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-theta and robo2

DIOPT Version :9

Sequence 1:NP_723103.1 Gene:DIP-theta / 33795 FlyBaseID:FBgn0051646 Length:606 Species:Drosophila melanogaster
Sequence 2:NP_001259868.1 Gene:robo2 / 44522 FlyBaseID:FBgn0002543 Length:1519 Species:Drosophila melanogaster


Alignment Length:445 Identity:102/445 - (22%)
Similarity:166/445 - (37%) Gaps:122/445 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   138 NVTVPVSREAVLQC-VVDNLQTYKIAWLRVDTQTILTIQNHVITKNHRMSITHAEKRAWILRIRD 201
            |..|.....|:::| ........:|:| |.:.||:      .:..|.|:.|.....    |.|::
  Fly   197 NTRVAQGEVALMECGAPRGSPEPQISW-RKNGQTL------NLVGNKRIRIVDGGN----LAIQE 250

  Fly   202 VKESDKGWYMCQIN--TDPMKSQVGYLDVVVPPDILDYPTSTDMVIREGSNVTLKCAATGSPTPT 264
            .::||.|.|.|.:.  ....:|...:|.|.|.|.::..|.:...|:  ||:|..:|...|.|.|.
  Fly   251 ARQSDDGRYQCVVKNVVGTRESATAFLKV
HVRPFLIRGPQNQTAVV--GSSVVFQCRIGGDPLPD 313

  Fly   265 ITWRR--EGGELIPLPNGAEAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVHFP 327
            :.|||  .||.: ||   ..........|.:..|...:||.|.|.|.|.: ..::...:|.||.|
  Fly   314 VLWRRTASGGNM-PL---RRVHVLEDRSLKLDDVTLEDMGEYTCEADNAV-GGITATGILTV
HAP 373

  Fly   328 PMIWI--QNQLVGAALTQNITLECQSEAYPKSINYWM--KNDTIIVPGERFVPETFESGYKITMR 388
            |...|  :||||  .:...:..|||:..:|:...||.  .|.::::||.|      :...::|:.
  Fly   374 PKFVIRPKNQLV--EIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYR------DGRMEVTLT 430

  Fly   389 ------LTIYEVDIQDFG-AYRCVAKNSLGDTDGAIKL-----YHIP----------QT------ 425
                  |:|.....:|.| ...|.|.|::|.......:     :.:|          ||      
  Fly   431 PEGRSVLSIARFAREDSGKVVTCNALNAVGSVSSRTVVSVDTQFELPPPIIEQGPVNQTLPVKSI 495

  Fly   426 -----TTMTTMAPTVS--INTVPVVLVKYNKE-------------QRY---------GSSQNSN- 460
                 .|:.|..|.||  ::.:|:.:.::.:.             ||:         .|::|.. 
  Fly   496 VVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAGALTISDLQRHEDEGLYTCVASNRNGKS 560

  Fly   461 -----------TNP------------YNFNPGNSQQNTK------LQRGKSNSKG 486
                       |||            |...||..|...|      |...:||..|
  Fly   561 SWSGYLRLDTPTNPNIKFFRAPELSTYPGPPGKPQMVEKGENSVTLSWTRSNKVG 615

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-thetaNP_723103.1 Ig 137..230 CDD:299845 22/94 (23%)
IG_like 137..230 CDD:214653 22/94 (23%)
IG_like 240..324 CDD:214653 24/85 (28%)
IGc2 247..310 CDD:197706 21/64 (33%)
Ig 327..419 CDD:299845 26/102 (25%)
IG_like 343..420 CDD:214653 19/90 (21%)
robo2NP_001259868.1 Ig1_Robo 90..185 CDD:143317
I-set 91..184 CDD:254352
I-set 190..279 CDD:254352 21/92 (23%)
Ig2_Robo 193..279 CDD:143201 21/92 (23%)
I-set 283..370 CDD:254352 26/93 (28%)
Ig 300..370 CDD:299845 21/74 (28%)
Ig 388..>457 CDD:299845 17/74 (23%)
I-set 479..561 CDD:254352 12/81 (15%)
Ig 496..561 CDD:143165 10/64 (16%)
FN3 588..681 CDD:238020 8/28 (29%)
FN3 <817..856 CDD:238020
fn3 864..952 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR12231
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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