DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-theta and dpr5

DIOPT Version :9

Sequence 1:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	296	Identity:	70/296 - (23%)
Similarity:	117/296 - (39%)	Gaps:	54/296 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GKLQRKREMPEISSRLIVATATAAVVSIICLSLALPGCAAQESDDEGELHHLDQMHHQHQDFIIG 90
            ||:......|:|:..::|....|.   ::.:.|..|               :|:
  Fly    24 GKVISNSRAPQIAHEMLVEYFMAL---LVIMGLTAP---------------VDK----------- 59

  Fly    91 ESEEHDHIAHHLAEMQNKDELLEDIRE--DTVVNAIPEKDLPKFGELLQNVTVPVSREAVLQCVV 153
            :|........|||..:....|:.|..:  |.|.:...:::          |...:...|.|.|.|
  Fly    60 QSRRSSQYFGHLAAAEELSNLIPDNYDAIDPVFDNTTDRE----------VIAALGTTARLHCRV 114

  Fly   154 DNLQTYKIAWLRVDTQTILTIQNHVITKNHRMSITHAEKR-AWILRIRDVKESDKGWYMCQINTD 217
            .:|....::|:|.....||||.....|.:.|....|.:.. .|:|:|..|::.|.|.|.||::|:
  Fly   115 RHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHIDNSDEWVLKIVSVQQRDAGVYECQVSTE 179

  Fly   218 PMKSQVGYLDVVV--PPDILDYPTSTDMVIREGSNVTLKCAATGSPTP--TITWRREGGELIPLP 278
            | |..:.|..|||  ...||   .:.::.|:.||::.|.|.|..:|.|  .:.|.::...:....
  Fly   180 P-KISLAYKLVVVTSKAQIL---ANRELFIQSGSDINLTCIAPQAPGPYTHMLWHKDTELVSDSA 240

  Fly   279 NGAEAV----AYNGSFLTIAKVNRLNMGAYLCIASN 310
            .|...|    ....|.|.|::|...:.|.|.|.|.|
  Fly   241 RGGIRVESEQQMKTSNLVISRVQHTDSGNYTCSADN 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	29/93 (31%)
		IG_like	137..230	CDD:214653	29/93 (31%)
		IG_like	240..324	CDD:214653	20/77 (26%)
		IGc2	247..310	CDD:197706	18/68 (26%)
		Ig	327..419	CDD:299845
		IG_like	343..420	CDD:214653
dpr5	NP_650080.3	V-set	95..191	CDD:284989	29/106 (27%)
		IG_like	98..179	CDD:214653	24/90 (27%)
		IG_like	206..278	CDD:214653	19/71 (27%)
		Ig	211..278	CDD:143165	17/66 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810