DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-theta and Ama

DIOPT Version :9

Sequence 1:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	95/343 - (27%)
Similarity:	152/343 - (44%)	Gaps:	50/343 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 DTVVNAIPEKDLPKFGELLQNVTVPVSREAVLQCVVDNLQTYKIAWLR----VDTQT-ILTIQNH 177
            |:|::|      |...::.::|...|.......|.|:.:....::|.:    .||.: :|:::|.
  Fly    27 DSVLSA------PVISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTNSVVLSMRNI 85

  Fly   178 VITKNHRMSITHAE-----KRAWILRIRDVKESDKGWYMCQI---NTDPMKSQVGYLDVVVPPDI 234
            :...:.|.::|..|     ...:..||::::.||.|.|.||:   .|:.:..::. |.:..||.|
  Fly    86 LSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLS-LQIKTPPVI 149

  Fly   235 LD-YPTSTDMVIREGSNVTLKCAATGSPTPTITWRRE-------GGELIPLPNGAEAVAYNGSFL 291
            .: .|.||  ::.||.|:.|.|.|.|.|.|||:|.||       ||.|:..|.           |
  Fly   150 AENTPKST--LVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGGHLLAEPT-----------L 201

  Fly   292 TIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPK 356
            .|..|:|::.|.|.|||.||......:.:.:.|.|.|.|.:|...:...::.:..|||..:.||.
  Fly   202 RIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQGYPA 266

  Fly   357 SINYWMKNDTIIVPGERF-VPETFESGYKITMRLTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLY 420
            ....|.||...:...... |..|..|....|..|.|..|..:|||.|.|.|.|.||..|..:.|:
  Fly   267 PTVVWHKNGVPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHLF 331

  Fly   421 HIPQTTTMTTMAPTVSIN 438
            .        |:.|..|::
  Fly   332 Q--------TVIPVPSLS 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	22/105 (21%)
		IG_like	137..230	CDD:214653	22/105 (21%)
		IG_like	240..324	CDD:214653	31/90 (34%)
		IGc2	247..310	CDD:197706	27/69 (39%)
		Ig	327..419	CDD:299845	28/92 (30%)
		IG_like	343..420	CDD:214653	25/77 (32%)
Ama	NP_731114.2	I-set	33..143	CDD:254352	23/110 (21%)
		Ig	37..127	CDD:299845	19/89 (21%)
		IG_like	154..234	CDD:214653	32/92 (35%)
		IGc2	161..223	CDD:197706	29/72 (40%)
		I-set	254..330	CDD:254352	25/75 (33%)
		IGc2	254..322	CDD:197706	22/67 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3058
SonicParanoid	1	1.000	-	-		X97
	6	5.850