DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-theta and dpr20

DIOPT Version :9

Sequence 1:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	79/369 - (21%)
Similarity:	138/369 - (37%)	Gaps:	87/369 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LTADAATIAARRQRRRAAGKLQRKREMPEISSRLI-------VATATAAVVSIICLSLALPGCAA 65
            |.|.:.|::.:.....:..|  :.....:|.|:.:       |||.::.:.|....|||.|...|
  Fly   149 LQAGSGTVSPKSSPDSSGHK--KNASFQQIGSQNVNALVPATVATTSSGLPSSSNASLATPTEPA 211

  Fly    66 QESDDEGELHHLDQMHHQHQDFIIGESEEHDHIAHHLAEMQNKDELLEDIREDTVVNAIPE---- 126
            :                .....::..|.......|.|::.|..|..:.:...||..:|...
  Fly   212 R----------------NRSTGLVRNSAVKVDSKHPLSKGQKTDAPMLNYIFDTFSSANKHHHHD 260

  Fly   127 -------KDLPKFGELLQNVTVPVSREAVLQCVVDNLQTYKIAWLRVDTQ----------TILTI 174
                   :|:.:.|: ..|:||.......|.|.:..||...::|:|.:||          .:||:
  Fly   261 QRYGPHFEDVQRIGQ-ATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTV 324

  Fly   175 QNHVITKNHRMSITHAEKRAWILRIRDVKESDKGWYMCQINTDP-----MKSQVGYLDVVVPPDI 234
            ..|..|.:.|..:.......|.|:|.:||:.|:..|.|||:|.|     :...|....|::..::
  Fly   325 GMHTYTGDKRYKMEFQYPNNWRLKITNVKKDDEAIYECQISTHPPRVIQINLHVNAPKVMIVDEV 389

  Fly   235 LDYPTSTDMVIREGSNVTLKC-----AATGSPTPTITWRR----------EGGELIP---LPNGA 281
            .| |.. :......|.:.|.|     |.|.|   .:.|:.          .||..:.   :.:||
  Fly   390 GD-PLQ-EKYYEIDSTLQLSCVVRNVAMTSS---VVFWKHMDNILNYDVTRGGVSVKTELMEDGA 449

  Fly   282 EAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVH 325
                  .|.|:|||:::.:.|.|.|..|.      .:...::||
  Fly   450 ------NSTLSIAKISKTDSGNYTCSISE------FQNFTIVVH 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	30/107 (28%)
		IG_like	137..230	CDD:214653	30/107 (28%)
		IG_like	240..324	CDD:214653	20/101 (20%)
		IGc2	247..310	CDD:197706	19/80 (24%)
		Ig	327..419	CDD:299845
		IG_like	343..420	CDD:214653
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	25/86 (29%)
		Ig	279..378	CDD:299845	27/98 (28%)
		Ig	400..471	CDD:299845	19/79 (24%)
		IG_like	402..480	CDD:214653	20/92 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810