DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-theta and dpr14

DIOPT Version :9

Sequence 1:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster

Alignment Length:	240	Identity:	70/240 - (29%)
Similarity:	106/240 - (44%)	Gaps:	40/240 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 KDELLEDIREDTVVNAIPEKDLPKFGE--LLQNVTVPVSREAVLQCVVDNLQTYKIAWL--RVDT 168
            :||.||      |......:..|.|.:  ...|::..:|....|.|.|::||...::|:  |.|.
  Fly    57 EDEELE------VTETTTHEPFPFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDD 115

  Fly   169 QTILTIQNHVITKNHRMSITHAEKRAWILRIRDVKESDKGWYMCQINTDPMKSQVGYLDVVVP-P 232
            .|::|...|..:.:.|.|:...|...|.|.|:...|.|:|.|.||:::.|....:.||.::|| .
  Fly   116 LTLITFGQHTYSGDSRYSLEFEEPNDWKLLIQFANERDEGPYECQVSSHPPLVLLVYLTIIVPHV 180

  Fly   233 DILDYPTST--DMVIREGSNVTLKCAATGSPTPT--ITWRR----------EGGELIP---LPNG 280
            :|||...|.  :...:.||.:.|:|..:..|.|:  ||||.          .||..:.   ||..
  Fly   181 EILDERGSATPEKYYKAGSTIELQCVISKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLPGR 245

  Fly   281 AEAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVH 325
            |.:..|      ||..||.:.|.|.|:..|.|..||      :||
  Fly   246 ALSRLY------IANANRQDTGNYTCMLGNEITETV------VVH 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	28/94 (30%)
		IG_like	137..230	CDD:214653	28/94 (30%)
		IG_like	240..324	CDD:214653	28/100 (28%)
		IGc2	247..310	CDD:197706	23/77 (30%)
		Ig	327..419	CDD:299845
		IG_like	343..420	CDD:214653
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	25/79 (32%)
		Ig	84..169	CDD:299845	25/84 (30%)
		IG_like	191..279	CDD:214653	29/100 (29%)
		Ig	201..274	CDD:143165	23/78 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810