DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-theta and Cntn4

DIOPT Version :9

Sequence 1:NP_723103.1 Gene:DIP-theta / 33795 FlyBaseID:FBgn0051646 Length:606 Species:Drosophila melanogaster
Sequence 2:NP_001103219.1 Gene:Cntn4 / 269784 MGIID:1095737 Length:1026 Species:Mus musculus


Alignment Length:409 Identity:99/409 - (24%)
Similarity:165/409 - (40%) Gaps:91/409 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   143 VSREAVLQCVVDNLQTYKIAWLRVDTQTILTI-----QNHVI---TKNHRMSITHAEKRAWI--- 196
            |||||.||...  |:.:|       |:|..|:     |..|:   ...|...:::    |||   
Mouse   110 VSREAKLQFAY--LENFK-------TRTRSTVSVRRGQGMVLLCGPPPHSGELSY----AWIFNE 161

  Fly   197 -----------------LRIRDVKESDKGWYMCQINTDPMKSQV------------GYLDVVVPP 232
                             |.|..|::||.|.|.|.:.......:|            |.:....|.
Mouse   162 YPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPK 226

  Fly   233 DILDYPTSTDMVIREGSNVTLKCAATGSPTPTITWRREGGELIPLPNGAEAVAYNGSFLTIAKVN 297
            ..:.:|.:  :...:|:.|.|:|.|.|:|.|||.|||..|:  |:...|.....|| .|.|....
Mouse   227 IEVQFPET--VPAEKGTTVKLECFALGNPVPTILWRRADGK--PIARKARRHKSNG-ILEIPNFQ 286

  Fly   298 RLNMGAYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINYWM 362
            :.:.|:|.|:|.|.....|:|..:.....|..:.|.|. :..|:.:::..||::...||....|:
Mouse   287 QEDAGSYECVAENSRGKNVAKGQLTFYAQPNWVQIIND-IHVAMEESVFWECKANGRPKPTYRWL 350

  Fly   363 KNDTIIVPGERFVPETFESGYKITMRLTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTT 427
            ||...::..:|.   ..|.|   |:.:||  |::.|.|.|:|||:|..|....:.:|..|.::..
Mouse   351 KNGDPLLTRDRI---QIEQG---TLNITI--VNLSDAGMYQCVAENKHGVIFSSAELSVIAESPD 407

  Fly   428 MT-TMAPTVSINTV---------------PVVLVKYNKE-----QRYGSSQNSNTNPYNFNPGNS 471
            .: |:...|::..|               ||...:..:|     :|...|::.|....|....::
Mouse   408 FSRTLLKRVTLVKVGGEVVIECKPKASPRPVYTWRKGREILRENERITISEDGNLRIINVTKSDA 472

  Fly   472 QQNTKLQR---GKSNSKGS 487
            ...|.:..   |.::|.|:
Mouse   473 GSYTCIATNHFGTASSTGN 491

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-thetaNP_723103.1 Ig 137..230 CDD:299845 28/126 (22%)
IG_like 137..230 CDD:214653 28/126 (22%)
IG_like 240..324 CDD:214653 27/83 (33%)
IGc2 247..310 CDD:197706 24/62 (39%)
Ig 327..419 CDD:299845 26/91 (29%)
IG_like 343..420 CDD:214653 22/76 (29%)
Cntn4NP_001103219.1 Ig 25..118 CDD:386229 6/7 (86%)
Ig 120..213 CDD:386229 20/105 (19%)
Ig 225..313 CDD:386229 29/92 (32%)
Ig 318..401 CDD:386229 26/91 (29%)
Ig 422..494 CDD:386229 11/70 (16%)
Ig6_Contactin-4 513..597 CDD:143261
FN3 597..690 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 685..710
FN3 703..792 CDD:238020
FN3 804..896 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 886..906
FN3 904..989 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.