DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-theta and Igsf9b

DIOPT Version :9

Sequence 1:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus

Alignment Length:	375	Identity:	101/375 - (26%)
Similarity:	160/375 - (42%)	Gaps:	71/375 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 NAIPE-----KDLPKFGELLQNVTVPVSREAVLQCVVDNLQT-----YKIAWLRVDTQTILTIQ- 175
            |.:|.     ::.|:|      ||.......||:|.|.:..|     |.:.|.:......:.|:
Mouse    19 NLVPGGAHGLREEPEF------VTARAGEGVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKF 77

  Fly   176 ----NHVITKNHRMSITHAEKRAWILRIRDVKESDKGWYMC-------QINTDPMKSQVGYLDVV 229
                .||..:....:..| :|.:  ||:..|:..|:|||.|       |.:|....|.| :|.:.
Mouse    78 GYYPPHVDPEYAGRASLH-DKAS--LRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWV-HLTIN 138

  Fly   230 VPPDILDYPTSTDMVIREGSNVTLKCAATGSPTPTITWRREGGELIPLPNGAEA--VAYNGSFLT 292
            .||...:.|... :..:||.::|:.|.|.|:|.|.:||.:||..|     ||.|  ...:|| ||
Mouse   139 APPTFTETPPQY-IEAKEGGSITMTCTAFGNPKPIVTWLKEGTLL-----GASAKYQVSDGS-LT 196

  Fly   293 IAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKS 357
            :..|:|.:.|||.|.|.: |.........|:|..||.|....:.:...::|:..|.|::||||.:
Mouse   197 VTSVSREDRGAYTCRAYS-IQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGN 260

  Fly   358 INY-WMKNDTIIVPGERFVPETFESGYKITMR------LTIYEVDIQDFGAYRCVAKNSLGDTDG 415
            :.| |...|..:.         |::..|:.:|      |.|:.|..:|.|.|.||..||||.:..
Mouse   261 LTYTWYWQDENVY---------FQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPS 316

  Fly   416 AIKLYHIPQTTTMTTMAPTVSINT-------------VPVVLVKYNKEQR 452
            |.....:.....:..|.|.:.:..             .|..:||:||:.|
Mouse   317 ASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGR 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	27/109 (25%)
		IG_like	137..230	CDD:214653	27/109 (25%)
		IG_like	240..324	CDD:214653	29/85 (34%)
		IGc2	247..310	CDD:197706	27/64 (42%)
		Ig	327..419	CDD:299845	29/98 (30%)
		IG_like	343..420	CDD:214653	26/83 (31%)
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273	20/76 (26%)
		I-set	141..227	CDD:369462	31/93 (33%)
		Ig	231..323	CDD:386229	28/100 (28%)
		Ig	<355..416	CDD:386229	6/12 (50%)
		Ig	440..504	CDD:319273
		FN3	512..607	CDD:238020
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910