Protein Alignment DIP-theta and wrk-1

DIOPT Version :9

• Sequence 1: NP_723103.1
• Gene: DIP-theta / 33795
• FlyBaseID: FBgn0051646
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001024651.1
• Gene: wrk-1 / 181093
• WormBaseID: WBGene00006942
• Length: 452
• Species: Caenorhabditis elegans
• Alignment Length: 508
• Identity: 99/508 - (19%)
• Similarity: 183/508 - (36%)
• Gaps: 139/508 - (27%)

  Fly   129 LPKFGELLQNVTVPVSREAVLQCVVDNLQTYKIAWLRVDTQTILTIQNHVITKNHRMSITHAEKR 193
            :.|.||.|           .|:|.|:: .:..|.| |.:|: ::.:.:.::.......|: .|..
 Worm    28 IAKEGESL-----------TLRCEVED-PSVAIIW-RKNTE-VVAVDDEILDTYGGYEIS-MEGS 77

  Fly   194 AWILRIRDVKESDKGWYMC---------------------QINTDPMKSQVGYLDVVVPPDILDY 237
            ..:|.|:.|:..:...|.|                     |::..|:        ||:.||...|
 Worm    78 TSVLTIKRVEPINSANYSCALAEPEVSVTFVIKVQVFKPTQVSVKPL--------VVISPDTGVY 134

  Fly   238 PTSTDMVIREG-SNVTLKC-AATGSPTPTITWRREGGELIPLPNGAEAVAYNGSFLTIAKVNRLN 300
            ..      |.| .|:.:.| ...|:|.|.:.|.::..:   ||...:. .:.|:.:.|.:|.:.:
 Worm   135 HA------RVGEKNLVITCHVKEGNPKPGVVWTKQAAK---LPEDIKR-EHGGARIVITEVKKHH 189

  Fly   301 MGAYLCIASN--GIPPTVSKRVMLIVHFPPMI--------WIQNQ--LVGAALTQNITLECQSEA 353
            .|.|.|:|.|  |     |.|..:.:|....:        |::|:  .:.....||.:..|..:.
 Worm   190 AGKYNCLAENIAG-----SDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDG 249

  Fly   354 YPKSINYWMKNDTIIVPGERFVPETFESGYKIT----MRLTIYEVDIQDFGAYRCVAKNSLGDTD 414
            .|.....|:.|...|...:....:|.|:..::.    ..||:.::..:.||.|.|...|.||...
 Worm   250 TPVPQVEWLFNGYKINFNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVT 314

  Fly   415 GAIKLYHI-----PQTTTMTTMAPTVSINTVPVVLVKYNKEQRYGSSQNSNTNPYNFNPGNSQQN 474
            ..:   |:     |...:......|.::.....:| :|....|.       .|..:|.|   :..
 Worm   315 AVV---HVSGRPGPPQLSFDESELTWTVRAFDKIL-EYQLCHRL-------ENADHFLP---EDC 365

  Fly   475 TKLQRGKSNSKGSDQSPSGLNNVFVGATSSLWNSQDHHSSSSSSSSASSRGRDHHQQQHHQQQQQ 539
            ..::..||::.|.|:                |.    |:...|:..       .|..::|.|.:.
 Worm   366 NSVRVKKSDNNGDDK----------------WT----HTIDLSTFL-------EHGNKYHVQLKA 403

  Fly   540 NHGSDHGASYRSDGKSPHLTNHDAKSLTDDLDRM--QDLKGWASRLSPISPIL 590
            .:....|:..:.             :|..:|.|:  ::.|| ||.:|.||.||
 Worm   404 RNALGWGSMAKD-------------ALHVELQRIEKEEAKG-ASIISIISSIL 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	17/113 (15%)
		IG_like	137..230	CDD:214653	17/113 (15%)
		IG_like	240..324	CDD:214653	21/87 (24%)
		IGc2	247..310	CDD:197706	16/64 (25%)
		Ig	327..419	CDD:299845	20/105 (19%)
		IG_like	343..420	CDD:214653	18/80 (23%)
wrk-1	NP_001024651.1	IG_like	25..113	CDD:214653	18/99 (18%)
		IGc2	31..96	CDD:197706	16/79 (20%)
		IG_like	132..212	CDD:214653	22/94 (23%)
		IGc2	142..202	CDD:197706	16/63 (25%)
		IG_like	235..320	CDD:214653	19/87 (22%)
		Ig	245..318	CDD:143165	16/75 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910