DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-theta and adgrl1.1

DIOPT Version :9

Sequence 1:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	XP_002660669.2	Gene:	adgrl1.1 / 100334775	ZFINID:	ZDB-GENE-130116-2	Length:	390	Species:	Danio rerio

Alignment Length:	261	Identity:	47/261 - (18%)
Similarity:	82/261 - (31%)	Gaps:	84/261 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 GELIPLPNGAEAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQL 336
            ||.:...:...:.|..| .|...|:|...:|.::|      |.|:.:
Zfish    37 GETVSFQHRVTSRAQPG-MLESGKMNNQTLGVFVC------PGTLVR------------------ 76

  Fly   337 VGAALTQNITLECQS--EAYPKSINYWMKNDTIIVPGERFVPETFESGYKITMRLTIYEVD-IQD 398
                     .||..|  ||...| ..|.|:.  :..|:|.          ..|..|.|..| :.:
Zfish    77 ---------VLEPSSVREAEDHS-GAWCKDP--LQAGDRL----------YVMPWTPYRTDMLYE 119

  Fly   399 FGAYRCVAKNSLGDTDGAIKLYHIPQTTTMTTMAPTVSINTVPVVLVKYNKEQRYGSSQNSNTNP 463
            :.::....:|.:..|      |.:|.....|.             .|.|:....|...:..|...
Zfish   120 YASWDDYIQNRVTTT------YKLPSRVDGTG-------------FVVYDGAVFYNKERTRNIVK 165

  Fly   464 YNFNPGNSQQNTKLQRGKS---NSKGSDQSPSGLNNVFVGATSSLWNSQDHHSSSSSSSSASSRG 525
            |:.       .|:::.|::   |:...|.||     ...|..|.:..:.|.|......::.::.|
Zfish   166 YDL-------RTRIKSGEAVIVNANYHDASP-----YHRGGKSDIDLAVDEHGLWVIYTTEANNG 218

  Fly   526 R 526
            |
Zfish   219 R 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845
		IG_like	137..230	CDD:214653
		IG_like	240..324	CDD:214653	11/51 (22%)
		IGc2	247..310	CDD:197706	9/37 (24%)
		Ig	327..419	CDD:299845	16/94 (17%)
		IG_like	343..420	CDD:214653	16/79 (20%)
adgrl1.1	XP_002660669.2	OLF	72..328	CDD:295358	37/219 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010