DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-theta and chl1b

DIOPT Version :9

Sequence 1:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	XP_017212175.2	Gene:	chl1b / 100318566	ZFINID:	ZDB-GENE-091105-1	Length:	1294	Species:	Danio rerio

Alignment Length:	306	Identity:	80/306 - (26%)
Similarity:	137/306 - (44%)	Gaps:	48/306 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 GELLQNVTVPVSREAVLQCVVDNLQTYKIAWLRVDTQTILTIQNHVITKNHRMSITHAEKRAWIL 197
            ||.||           |:|:.:...|.|:.|:::...   .:...|:.::|          ..:|
Zfish   276 GEDLQ-----------LECIAEGFPTPKVEWVKIGFN---KLPERVVVESH----------GKLL 316

  Fly   198 RIRDVKESDKGWYMCQINTDPMKSQVGYLDVVV--PPDILDYPTSTDMVIREGSNVTLKCAATGS 260
            .:..|.|.|:|.|||:.. :|....|.:..|.|  ||:....|.|  .::..|::|.:||...|:
Zfish   317 TVEMVNEEDEGKYMCRAK-NPHGEVVHHFHVTVEEPPEFEIEPQS--QLVTIGADVLIKCVVKGN 378

  Fly   261 PTPTITWRREGGELIPLPNGAEAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVH 325
            |.||:.||..|..|..:|.....:..:|: ::|...|..|...|.|.|:|.....::...::|::
Zfish   379 PQPTVGWRVNGRPLNEVPTSNRKILKDGT-ISIHNANPENSAVYQCEATNKHGTILANANIMIMN 442

  Fly   326 FPPMIWIQNQLVGAALT-QNITLECQSEAYPKSINYWMKNDTI-IVPGERFVPETFESGYKITMR 388
            ..|:|..:|.|...|:. :::.:.|:..:.|.|...|.|.|:. .|.||||.  ..::|     .
Zfish   443 IQPLILTENNLQYMAVEGKSVVMHCKVFSSPASSITWSKADSANAVEGERFT--VHQNG-----S 500

  Fly   389 LTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTTMTTMAPT 434
            |.|:.|..:|.|.|.|.|:|    |:|.:.:     ..|:....||
Zfish   501 LEIHNVMKEDMGEYSCFAQN----TEGKVAI-----AATLEVKDPT 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	19/92 (21%)
		IG_like	137..230	CDD:214653	19/92 (21%)
		IG_like	240..324	CDD:214653	22/83 (27%)
		IGc2	247..310	CDD:197706	20/62 (32%)
		Ig	327..419	CDD:299845	28/93 (30%)
		IG_like	343..420	CDD:214653	23/77 (30%)
chl1b	XP_017212175.2	Ig	61..135	CDD:325142
		Ig	138..231	CDD:325142
		Ig	279..348	CDD:325142	20/93 (22%)
		Ig	366..438	CDD:325142	21/72 (29%)
		IG	454..533	CDD:214652	25/94 (27%)
		I-set	538..628	CDD:333254	80/306 (26%)
		FN3	632..722	CDD:238020
		FN3	734..815	CDD:238020
		FN3	832..931	CDD:238020
		fn3	942..1022	CDD:306538
		FN3	1070..1142	CDD:214495
		Bravo_FIGEY	1196..1279	CDD:316405
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100