DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and VTCN1

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_011540445.2	Gene:	VTCN1 / 79679	HGNCID:	28873	Length:	332	Species:	Homo sapiens

Alignment Length:	206	Identity:	42/206 - (20%)
Similarity:	81/206 - (39%)	Gaps:	58/206 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 VGRDAFLTCVVQ---DLGPYKVAWLR----------VDTQTILTIQNHVITKN-----QRIGIAN 102
            :|.|..|:|..:   .|....:.||:          .:.:..|:.|:.:....     .::.:.|
Human    98 IGEDGILSCTFEPDIKLSDIVIQWLKEGVLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGN 162

  Fly   103 SEHKTWTMRIKDIKESDKGWYMCQINTDPMKS------QMGYLDVVVPPDI-LDYPTSTDMVVRE 160
            :     ::|:|:::.:|.|.|.|.|.|...|.      :.|...:   |:: :||..|::
Human   163 A-----SLRLKNVQLTDAGTYKCYIITSKGKGNANLEYKTGAFSM---PEVNVDYNASSE----- 214

  Fly   161 GSNVTLKC-AATGSPEPTITWRRE----------SGVPIELATGEEVMSIEGTDLVIPNVRRHHM 214
                ||:| |....|:||:.|..:          |....||.:....|.:..   |:.||..::
Human   215 ----TLRCEAPRWFPQPTVVWASQVDQGANFSEVSNTSFELNSENVTMKVVS---VLYNVTINN- 271

  Fly   215 GAYLCIASNGV 225
             .|.|:..|.:
Human   272 -TYSCMIENDI 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	20/108 (19%)
		IG_like	51..137	CDD:214653	19/104 (18%)
		IG_like	153..237	CDD:214653	19/84 (23%)
		Ig	161..224	CDD:299845	17/73 (23%)
		IG_like	252..335	CDD:214653
		Ig	258..333	CDD:143165
VTCN1	XP_011540445.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910