DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and opcml

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001072487.1	Gene:	opcml / 779942	XenbaseID:	XB-GENE-5831850	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	333	Identity:	101/333 - (30%)
Similarity:	160/333 - (48%)	Gaps:	38/333 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CALSVILLLILMSQQCYPQRVEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVAWL 77
            |.:....|.:|:|....|.|..       |..|...:.|:|...|..|.|.|.| |....:||||
Frog    15 CWMFGAALTVLLSITGVPVRSG-------DAGFPKAMDNVTVRQGDSAILRCTV-DNRVTRVAWL 71

  Fly    78 RVDTQTILTIQNHVITKNQRIGIANSEHKTWTMRIKDIKESDKGWYMCQINTD--PMKSQMGYLD 140
              :..|||...|...:.:.|:.:..:....:::.|:::...|:|.|.|.:.||  |..|:: :|.
Frog    72 --NRSTILYTGNDKWSIDPRVVLLANTKSQYSIEIQNVDIYDEGPYTCSVQTDNHPKTSRV-HLI 133

  Fly   141 VVVPPDILDYPTSTDMVVREGSNVTLKCAATGSPEPTITWRRESGVPIELATGEEVMSIEGTDLV 205
            |.|.|.||:  .|:|:.|.|||.|.|:|.|||.|||.:|||..:|......:.:|.:.|.|
Frog   134 VQVAPQILN--ISSDITVNEGSTVALRCLATGRPEPAVTWRHFTGKSHRFVSDDEYLEITG---- 192

  Fly   206 IPNVRRHHMGAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKS 270
               :.|...|.|.|.|:|.|.....:::.:.|::||.|: ..:..||..|:...|.|.:.|.|.:
Frog   193 ---ITRDQSGQYECSAANDVSAPDIRKVRVTVNYPPYIS-DTRNTGASLGQKGILRCSASAVPLA 253

  Fly   271 INYWTRERGEIVPPGGKYSANVTEIGGYRNSMRLHINPLT-----QAEFGSYRCVAKNSLGDTDG 330
            ...|.||...:        ||  .:.|.|...:.|::.||     :.::|:|.|||.|.||:::.
Frog   254 EFQWYREETRL--------AN--GLDGVRIENKDHMSILTFFNVSEKDYGNYTCVASNKLGNSNA 308

  Fly   331 TIKLYRIP 338
            ::.||..|
Frog   309 SVILYAGP 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	27/91 (30%)
		IG_like	51..137	CDD:214653	26/87 (30%)
		IG_like	153..237	CDD:214653	29/83 (35%)
		Ig	161..224	CDD:299845	23/62 (37%)
		IG_like	252..335	CDD:214653	24/87 (28%)
		Ig	258..333	CDD:143165	22/79 (28%)
opcml	NP_001072487.1	Ig	46..134	CDD:325142	27/91 (30%)
		Ig_3	138..207	CDD:316449	30/77 (39%)
		ig	228..312	CDD:278476	25/94 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060