DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and igsf9bb

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	356	Identity:	91/356 - (25%)
Similarity:	145/356 - (40%)	Gaps:	89/356 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 DPKFSSPIVNMTAPVGRDAFLTC-VVQDLG--PYKVAWLRVDTQTILTIQ-----NHVITKNQRI 98
            :|:|      :|:..|....|.| ||..|.  ||.|.|.:........|.     .||  ..:..
Zfish    29 EPQF------VTSRAGETVILGCDVVHPLNGQPYVVEWFKFGVPIPFFINFRFYPPHV--DPEYA 85

  Fly    99 GIANSEHKTWTMRIKDIKESDKGWYMCQINTDPMKSQMGY----------LDVVVPPDILDYPTS 153
            |.| |.|...::||:.::..|:|||.|::    :..:..|          |.|..||...|.|..
Zfish    86 GRA-SLHGKSSLRIERVRSEDQGWYECKV----LMLEQQYHTFHNGSWVHLTVNAPPTFTDTPPQ 145

  Fly   154 TDMVVREGSNVTLKCAATGSPEPTITWRRESGVPIELATGEEVMSIEGTDLVIPNVRRHHMGAYL 218
            . :..:||.::||.|.|.|:|:|:::|.|| |.|::.:|..:|.  :|: |.:.::.|...|||.
Zfish   146 Y-VEAKEGGSITLSCTAFGNPKPSVSWLRE-GNPVQDSTKYKVS--DGS-LTLVSISREDRGAYT 205

  Fly   219 CIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINY-WTRERGEIV 282
            |.|.:....:| ....|:|..||.|....:.|.....:.....|::||||.::.| |..|...:.
Zfish   206 CRAYSEQGEAV-HTTRLLVQGPPFIVSPPENITVNISQDAFFTCQAEAYPGNLTYTWFWEEDNVF 269

  Fly   283 PPGGKYSANVTEIGGYRNSMR----------LHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYRI 337
                           ::|.::          |.|:.:...:.|.|.|...||||.
Zfish   270 ---------------FKNDLKRRVSILIDGSLIISQVKPEDAGKYTCSPSNSLGR---------- 309

  Fly   338 PPNAVNYVENFEARHKGKKRTKSSESHHPAR 368
            ||:|..|:                ..|:|||
Zfish   310 PPSASAYL----------------TVHYPAR 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	27/107 (25%)
		IG_like	51..137	CDD:214653	25/93 (27%)
		IG_like	153..237	CDD:214653	26/83 (31%)
		Ig	161..224	CDD:299845	23/62 (37%)
		IG_like	252..335	CDD:214653	18/93 (19%)
		Ig	258..333	CDD:143165	18/85 (21%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	27/91 (30%)
		Ig	41..113	CDD:143165	23/74 (31%)
		IG_like	144..223	CDD:214653	26/84 (31%)
		IGc2	151..208	CDD:197706	23/60 (38%)
		I-set	227..319	CDD:254352	25/132 (19%)
		Ig	<263..319	CDD:299845	15/96 (16%)
		Ig_2	326..414	CDD:290606
		IG_like	329..403	CDD:214653
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010