DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and dscama

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_021334866.1	Gene:	dscama / 568643	ZFINID:	ZDB-GENE-050310-7	Length:	2025	Species:	Danio rerio

Alignment Length:	373	Identity:	97/373 - (26%)
Similarity:	156/373 - (41%)	Gaps:	56/373 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CQCRKQTCALSVILLLILMSQQCYPQRVEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLG 70
            |.|......:|            |..|:.|.....:     .|:.|:||..|.|.::.|.|....
Zfish   485 CTCNNSAGTVS------------YQARINVRGSADI-----RPMKNLTAIAGWDMYIHCHVIGYP 532

  Fly    71 PYKVAWLRVDTQTILTIQNHVITKNQRIGIANSEHKTWTMRIKDI-KESDKGWYMCQINTDP--M 132
            .|.:.|.:         .::::..|.|   ..:.....|:::.:: ||.|:|.|.|.:...|  .
Zfish   533 YYSIKWFK---------NSNLLPFNDR---QRAFENNGTLKLLNVQKELDEGEYSCHVQVQPQLF 585

  Fly   133 KSQMGYLDVVVPPDI--LDYPTSTDMVVREGSNVTLKCAATGSPEP-TITWRRESGVPIELATGE 194
            |:|..::.|.|||.|  .::|..:     .|..|.:.|.......| :|||.:: |..|..:.|.
Zfish   586 KNQSVHVTVKVPPFIQPFEFPRYS-----IGHRVFVPCVVRSGDLPISITWEKD-GKSINASLGV 644

  Fly   195 EVMSIEGT-DLVIPNVRRHHMGAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGV 258
            .:.:|:.| .|.|.|::|.|.|.|.|||.|.. ..|..:..|:|..||...||.|....:.||.|
Zfish   645 TIDNIDFTSSLRISNLQRVHNGTYTCIAQNDA-AVVKYQSQLIVRVPPRFKVQPQDQDGIYGKSV 708

  Fly   259 TLDCESEAYPKSINYWTRERGEIVPPGGKYSANVTEIGGYRNSM----RLHINPLTQAEFGSYRC 319
            .|:|.::..|:....|...:|..||.....:.|    .|:|..:    .|.|..:.:.:.|.|.|
Zfish   709 ILNCSADGEPRPTIEWKYSKGAGVPQFQPIALN----SGFRVQLLGNGSLLIKHVLEEDAGYYLC 769

  Fly   320 VAKNSLGDTDGTIKLY---RIPPNAVNYVENFEARHKGKKRTKSSESH 364
            ...|.:| .|.:..:|   :||....:|..|..|. ||:|...|.::|
Zfish   770 KVSNDVG-ADVSKSMYLNVKIPAMITSYPNNSLAT-KGEKIEMSCKAH 815

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	21/92 (23%)
		IG_like	51..137	CDD:214653	21/88 (24%)
		IG_like	153..237	CDD:214653	25/85 (29%)
		Ig	161..224	CDD:299845	22/64 (34%)
		IG_like	252..335	CDD:214653	21/86 (24%)
		Ig	258..333	CDD:143165	19/78 (24%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352
		IG_like	321..402	CDD:214653
		I-set	408..502	CDD:333254	5/28 (18%)
		IGc2	524..579	CDD:197706	13/66 (20%)
		Ig	614..679	CDD:319273	22/66 (33%)
		Ig_DSCAM	708..787	CDD:143211	20/83 (24%)
		Ig	805..898	CDD:325142	4/11 (36%)
		FN3	894..988	CDD:238020
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810