DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and igsf9ba

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	461	Identity:	103/461 - (22%)
Similarity:	168/461 - (36%)	Gaps:	122/461 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 DPKFSSPIVNMTAPVGRDAFLTCVVQ-----DLGPYKVAWLRVDTQTILTIQ-----NHVITKNQ 96
            :|:|      :||..|....|.|.|.     ...||.|.|.:........|.     .||  ..:
Zfish    29 EPQF------VTARAGESVVLGCDVSHPLNGQQTPYVVEWFKFGVPIPFFINFRFYPPHV--DPE 85

  Fly    97 RIGIANSEHKTWTMRIKDIKESDKGWYMCQINTDPMKSQMG--------YLDVVVPPDILDYPTS 153
            ..|.| |.|...:::|:.::..|:|||.|::..  ::.|..        :|.|..||...|.|..
Zfish    86 YAGRA-SLHGKASLQIEQVRSEDQGWYECRVLM--LEQQYDTFHNGSWVHLTVNAPPTFSDTPPQ 147

  Fly   154 TDMVVREGSNVTLKCAATGSPEPTITWRRESGVPIELATGEEVMSIEGTDLVIPNVRRHHMGAYL 218
            . :..|||.::||.|.|.|:|:|.:||.||.    :..|.....::....|.:..:.|...|||.
Zfish   148 Y-VEAREGGSITLTCTAFGNPKPVVTWLREG----DQLTSTRKYTVSDGSLTVQAITREDRGAYS 207

  Fly   219 CIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINY-WTRERGEIV 282
            |.|.:....:: ....|:|..||.|....:.|.....:.....|::||||.::.| |..|...:.
Zfish   208 CRAHSDQGEAL-HTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEEDNVY 271

  Fly   283 PPGGKYSANVTEIGGYRNSMRLHIN----------PLTQAEFGSYRCVAKNSLGDTDGTIKLYRI 337
                           ::|.::|.:.          .:...:.|.|.|...||||          |
Zfish   272 ---------------FKNDLKLRVRIFIDGTLIIYRVKPEDAGKYTCSPSNSLG----------I 311

  Fly   338 PPNAVNYVE-NFEAR--------HKGKK----------------RTKSSESHHPARAQEHSG-ED 376
            .|:|..|:. .:.||        :..:|                ..:..:..:|.|.:::.| ..
Zfish   312 SPSASAYLTVQYPARVVNMPPVIYVPRKLSGIIRCPVDANPPVTSVRWEKDGYPLRIEKYPGWSQ 376

  Fly   377 MENPGKRKADL---SLGAESI--------------------DSIYGNSAAGSRRRQDLGGVLLLL 418
            |.:...|.|::   |||..:.                    |..|.|...|...||:.|..  |:
Zfish   377 MTDGSIRVAEVTEDSLGTYTCVPYNVLGTMGQSPPATLVLKDPPYFNVRPGGEYRQEAGRE--LV 439

  Fly   419 LPVAVA 424
            :|.|.:
Zfish   440 IPCAAS 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	25/107 (23%)
		IG_like	51..137	CDD:214653	24/95 (25%)
		IG_like	153..237	CDD:214653	23/83 (28%)
		Ig	161..224	CDD:299845	20/62 (32%)
		IG_like	252..335	CDD:214653	17/93 (18%)
		Ig	258..333	CDD:143165	17/85 (20%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652	25/93 (27%)
		I-set	139..225	CDD:254352	26/91 (29%)
		I-set	229..321	CDD:333254	24/116 (21%)
		Ig	345..415	CDD:325142	9/69 (13%)
		Ig	438..503	CDD:319273	3/8 (38%)
		FN3	511..606	CDD:238020
		FN3	622..706	CDD:238020
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810