DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and paplna

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	229	Identity:	66/229 - (28%)
Similarity:	97/229 - (42%)	Gaps:	33/229 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 SPIVNMTAPVGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVITKNQRI-GIANSEHKTWTM 110
            ||:|.  |..|:.|.|.|.|          |.|.....:||  |.....|.: .:.:|:|...|:
Zfish   952 SPLVE--ARAGQTAKLQCSV----------LPVSAIHAVTI--HWSRAGQPLNSLRHSQHSDGTL 1002

  Fly   111 RIKDIKESDKGWYMCQINTDPMKSQMGYLDVVVPPDILDYPTSTDMVVREGSNVTLKCAATGSPE 175
            .||.:...|.|.|.|.: ||..|.:...:.:.|..|:.......|:.|.:||...|.|..||. .
Zfish  1003 VIKQLTADDSGLYTCTV-TDAQKFEERQVQLRVLGDLRITKAPIDVDVVQGSTAQLACVVTGE-N 1065

  Fly   176 PTITWRRESGVPIELATGEEV-MSIEGTDLVIPNVRRHHMGAYLCIASNG-VPPSVSKRITLVVH 238
            ..:.|.| :|||:. ..|..| :|.:|| |::.||:....|.|.|.|..| :..|.:..|.|..
Zfish  1066 VNVGWSR-NGVPVR-PDGHRVHVSADGT-LILNNVQSVDEGTYTCNAYTGTLSVSAAAEIRLAK- 1126

  Fly   239 FPPMITVQNQLIGAVEGKGVTLDCESEAYPKSIN 272
                 |.|..:.|   |:..:.||..:  |:..|
Zfish  1127 -----TPQQDIDG---GQFSSSDCVDQ--PELAN 1150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	24/90 (27%)
		IG_like	51..137	CDD:214653	24/86 (28%)
		IG_like	153..237	CDD:214653	29/85 (34%)
		Ig	161..224	CDD:299845	23/63 (37%)
		IG_like	252..335	CDD:214653	5/21 (24%)
		Ig	258..333	CDD:143165	4/15 (27%)
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449
		IGc2	960..1022	CDD:197706	21/74 (28%)
		I-set	1039..1121	CDD:333254	27/85 (32%)
		PLAC	1142..1173	CDD:312271	3/11 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900