DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-eta and robo4

DIOPT Version :9

Sequence 1:NP_001188701.2 Gene:DIP-eta / 33793 FlyBaseID:FBgn0031725 Length:450 Species:Drosophila melanogaster
Sequence 2:XP_689255.3 Gene:robo4 / 560765 ZFINID:ZDB-GENE-020809-1 Length:1134 Species:Danio rerio


Alignment Length:352 Identity:81/352 - (23%)
Similarity:137/352 - (38%) Gaps:102/352 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 LMSQQCYPQRVEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVAWLR--------- 78
            |:|:...|:.|..|::|:|             .||..|.|:|..:......:.|||         
Zfish    64 LVSEINLPRIVHHPSDVVV-------------RVGSPATLSCRAEGNPEPTIQWLRNGQPLDTDK 115

  Fly    79 VDTQTILTI-----------------QNH-----VITKNQRIGIANSEHKTWTMRIKDIKESDKG 121
            :|.|:...:                 |:|     .|..|   .|.|:..:..::.|..::|    
Zfish   116 MDAQSQPIVLPDGSLFFFSVVPGRKGQSHEAVYACIAHN---SIGNATSRNASLHIAALRE---- 173

  Fly   122 WYMCQINTDPMKSQMGYLDVVVPPDILDYPTSTDMVVREGSNVTLKCA-ATGSPEPTITWRRESG 185
                              |..|.|        :|:.|..|...|:.|: ..|.|||.:|||:: |
Zfish   174 ------------------DFRVQP--------SDVEVAIGEMATINCSPPVGHPEPNVTWRKD-G 211

  Fly   186 VPIELATGEEVMSIEGTDLVIPNVRRHHMGAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLI 250
            :.|. ::.|....::| .|:|...:::..|.|.|||||.:....|:...|.|...|::..:.:.:
Zfish   212 ILIN-SSNEHYTELKG-KLIIAPAQKNDSGVYSCIASNMIGVRESRAARLSVLAKPVLLRKPEDV 274

  Fly   251 GAVEGKGVTLDCESEAYPKSINYWTRERGEIVPPGGKYSANVTEIGGYRNSMRLHINPLTQAEFG 315
            ....|:.....||::..|.....|:||:|.:  |.|:|..|..      :|:::|.  :|..:.|
Zfish   275 SVQLGESAQFFCEADGDPMPSIEWSREQGPL--PNGRYLINPD------HSLQIHY--VTAQDMG 329

  Fly   316 SYRCVAKNSLG-----------DTDGT 331
            .|.|..:|.||           |..||
Zfish   330 RYSCTVENKLGVSVASAQLLVEDAGGT 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-etaNP_001188701.2 Ig 51..141 CDD:299845 18/120 (15%)
IG_like 51..137 CDD:214653 18/116 (16%)
IG_like 153..237 CDD:214653 27/84 (32%)
Ig 161..224 CDD:299845 22/63 (35%)
IG_like 252..335 CDD:214653 24/91 (26%)
Ig 258..333 CDD:143165 23/85 (27%)
robo4XP_689255.3 Ig1_Robo 70..169 CDD:143317 21/114 (18%)
I-set 71..168 CDD:254352 21/112 (19%)
I-set 175..261 CDD:254352 29/96 (30%)
Ig2_Robo 177..261 CDD:143201 29/94 (31%)
I-set 265..350 CDD:254352 22/94 (23%)
Ig 282..350 CDD:299845 20/77 (26%)
FN3 373..448 CDD:214495
FN3 472..560 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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