DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and Cadm1

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001297770.1	Gene:	Cadm1 / 54725	MGIID:	1889272	Length:	474	Species:	Mus musculus

Alignment Length:	314	Identity:	79/314 - (25%)
Similarity:	124/314 - (39%)	Gaps:	50/314 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 NMTAPVGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVITKNQRIGIANSEHKTWTMRIKDI 115
            ::|...|..|.::|.|.......:..|..:.|||. .::....|:.|..:.|.......:.:.::
Mouse    54 DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIY-FRDFRPLKDSRFQLLNFSSSELKVSLTNV 117

  Fly   116 KESDKGWYMCQINTDPMKSQMGYLDVVVPPDILDYPTSTDMVVREGSNVTLKCAATGS-PEPTIT 179
            ..||:|.|.||:.|||.:.....:.|:|||..|......|..| ||..:.:.|.|..| |..||.
Mouse   118 SISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAV-EGEEIEVNCTAMASKPATTIR 181

  Fly   180 W---RRESGVPIELATGEEVMSIEGTDLVIPNVRRHHMGAYLCIASNGVP-------PSVSKRIT 234
            |   .:|.....|:....::.::  |..::..|.:.         .:|||       |:|:..:.
Mouse   182 WFKGNKELKGKSEVEEWSDMYTV--TSQLMLKVHKE---------DDGVPVICQVEHPAVTGNLQ 235

  Fly   235 ----LVVHFPPMITVQ--NQLIGAV-EGKGVTLDCESEAYPKSINY-WTRERGEIVPPGGKYSAN 291
                |.|.:.|.:.:|  ..|.|.. ||....|.||:...|:.:.. |.|...| :|.....|
Mouse   236 TQRYLEVQYKPQVHIQMTYPLQGLTREGDAFELTCEAIGKPQPVMVTWVRVDDE-MPQHAVLS-- 297

  Fly   292 VTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLY------RIPP 339
                     ...|.||.|.:.:.|:|||.|.|.:|.......||      .|||
Mouse   298 ---------GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPP 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	21/89 (24%)
		IG_like	51..137	CDD:214653	21/85 (25%)
		IG_like	153..237	CDD:214653	21/98 (21%)
		Ig	161..224	CDD:299845	12/66 (18%)
		IG_like	252..335	CDD:214653	22/84 (26%)
		Ig	258..333	CDD:143165	20/75 (27%)
Cadm1	NP_001297770.1	Ig1_Necl-2	49..143	CDD:143289	21/89 (24%)
		Ig2_Necl-2	164..245	CDD:143291	18/91 (20%)
		IG_like	255..333	CDD:214653	25/89 (28%)
		4.1m	427..445	CDD:128590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910