DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-eta and Ntm

DIOPT Version :9

Sequence 1:NP_001188701.2 Gene:DIP-eta / 33793 FlyBaseID:FBgn0031725 Length:450 Species:Drosophila melanogaster
Sequence 2:XP_017451354.1 Gene:Ntm / 50864 RGDID:620958 Length:367 Species:Rattus norvegicus


Alignment Length:339 Identity:101/339 - (29%)
Similarity:163/339 - (48%) Gaps:48/339 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 DPKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVITKNQRIGIANSEHK 106
            |..|...:.|:|...|..|.|.|.: |....:||||  :..|||...|.....:.|:.:.::...
  Rat    35 DATFPKAMDNVTVRQGESATLRCTI-DNRVTRVAWL--NRSTILYAGNDKWCLDPRVVLLSNTQT 96

  Fly   107 TWTMRIKDIKESDKGWYMCQINTD--PMKSQMGYLDVVVPPDILDYPTSTDMVVREGSNVTLKCA 169
            .:::.|:::...|:|.|.|.:.||  |..|:: :|.|.|.|.|::  .|:|:.:.||:|::|.|.
  Rat    97 QYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRV-HLIVQVSPKIVE--ISSDISINEGNNISLTCI 158

  Fly   170 ATGSPEPTITWRRESGVPIELATGEEVMSIEGTDLVIPNVRRHHMGAYLCIASNGVPPSVSKRIT 234
            |||.||||:|||..|...:...:.:|.:.|:|       :.|...|.|.|.|||.|...|.:|:.
  Rat   159 ATGRPEPTVTWRHISPKAVGFVSEDEYLEIQG-------ITREQSGEYECSASNDVAAPVVRRVK 216

  Fly   235 LVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRERGEIVPPGGKYSANVTEIGGYR 299
            :.|::||.|: :.:..|...|:..||.||:.|.|.:...|.::...:|.  ||....|      .
  Rat   217 VTVNYPPYIS-EAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVE--GKKGVKV------E 272

  Fly   300 NS---MRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYRI---------------------PPN 340
            |.   .||....:::.::|:|.|||.|.||.|:.:|.|:.:                     .|.
  Rat   273 NRPFLSRLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLLQEVKTTALTPWKGPG 337

  Fly   341 AVNYVENFEARHKG 354
            ||:.|.|..:|..|
  Rat   338 AVSEVNNGTSRRAG 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-etaNP_001188701.2 Ig 51..141 CDD:299845 26/91 (29%)
IG_like 51..137 CDD:214653 25/87 (29%)
IG_like 153..237 CDD:214653 31/83 (37%)
Ig 161..224 CDD:299845 24/62 (39%)
IG_like 252..335 CDD:214653 25/85 (29%)
Ig 258..333 CDD:143165 23/77 (30%)
NtmXP_017451354.1 Ig 44..132 CDD:416386 26/91 (29%)
Ig strand A' 44..49 CDD:409353 2/4 (50%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 1/4 (25%)
FR2 64..70 CDD:409353 4/7 (57%)
Ig strand C 64..70 CDD:409353 4/7 (57%)
CDR2 71..83 CDD:409353 4/11 (36%)
Ig strand C' 72..76 CDD:409353 2/3 (67%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 6/33 (18%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 2/3 (67%)
Ig strand G 123..132 CDD:409353 3/9 (33%)
FR4 125..132 CDD:409353 2/7 (29%)
Ig_3 136..205 CDD:404760 28/77 (36%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand F 197..205 CDD:409353 4/7 (57%)
Ig 223..307 CDD:416386 27/92 (29%)
putative Ig strand A 223..229 CDD:409353 2/6 (33%)
Ig strand B 239..243 CDD:409353 2/3 (67%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 2/3 (67%)
Ig strand F 292..297 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166337215
Domainoid 1 1.000 59 1.000 Domainoid score I10374
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4382
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8971
orthoMCL 1 0.900 - - OOG6_104123
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
1110.800

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