back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-eta and LRIT3

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_940908.3	Gene:	LRIT3 / 345193	HGNCID:	24783	Length:	679	Species:	Homo sapiens

Alignment Length:	398	Identity:	79/398 - (19%)
Similarity:	138/398 - (34%)	Gaps:	123/398 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 KTWTMRIK------DIKES-------DKGWYM-CQIN---------------TDPMKS------- 134
            ::||..:.      |:..|       |..|:. |.|:               .||:.:
Human   174 ESWTHLVSTPSGVLDLSPSRIILGLQDNPWFCDCHISKMIELSKVVDPAIVLLDPLMTCSEPERL 238

  Fly   135 -----QMGYLDVVVPPDILDYPTSTDMVVREGSNVTLKCAATGSPEPTITWRRESGVPIELATGE 194
                 |...|:..:.|.::  .::|.::...||||.|:|.|||.|.|.|||.|....|:.....:
Human   239 TGILFQRAELEHCLKPSVM--TSATKIMSALGSNVLLRCDATGFPTPQITWTRSDSSPVNYTVIQ 301

  Fly   195 E---------VMSIEGTDLVIPNVRRHHMGAYLCIASN--GVPPSVSKRITLVVHFPPMITVQNQ 248
            |         :||:.|       :.....|.|.|.|.|  |:..:|   :|:.|
Human   302 ESPEEGVRWSIMSLTG-------ISSKDAGDYKCKAKNLAGMSEAV---VTVTV----------- 345

  Fly   249 LIGAVEGKGVTLDCESEAYPKSINYWTRERGE-IVPPGGKYSANVTEIGGYRNSMRLHINPLTQA 312
                   .|:|    :...|...:..|.:..| .|.||...|.:|:....|          |..:
Human   346 -------LGIT----TTPIPPDTSERTGDHPEWDVQPGSGRSTSVSSASSY----------LWSS 389

  Fly   313 EFGSYRCVAKNSLGDTDGTIKLYRIPPNAVNY-VENFEARHKGKKRTKS-SESHHPARAQEHSGE 375
            .|......:.::|.           ||:..:: :..|.:.......|.| |.|.....|.:.|.:
Human   390 SFSPTSSFSASTLS-----------PPSTASFSLSPFSSSTVSSTTTLSTSISASTTMANKRSFQ 443

  Fly   376 DMENPGKRKADLSLGAESIDSIYGNSAAGSRRRQDLGGVLLLLLPVAVAVAMSLATAGVMRETQM 440
             :...|||...::.....:      ..|.:.::::|.   ||...:......::....|:.||:.
Human   444 -LHQGGKRNLKVAKNGSKL------PPASTSKKEELA---LLDQTMLTETNAAIENLRVVSETKE 498

  Fly   441 TLPPQTLT 448
            ::   |||
Human   499 SV---TLT 503

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.