DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-eta and Sdk1

DIOPT Version :9

Sequence 1:NP_001188701.2 Gene:DIP-eta / 33793 FlyBaseID:FBgn0031725 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_808547.3 Gene:Sdk1 / 330222 MGIID:2444413 Length:2193 Species:Mus musculus


Alignment Length:329 Identity:81/329 - (24%)
Similarity:130/329 - (39%) Gaps:49/329 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 PQRVEVPAEVIVDPKFSS-PIVNMTAPVGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVIT 93
            |.|......:|..|.|:: |...:...|.....:.|....:....:.|.: |...:..:|     
Mouse   355 PARARAFLSIIEPPYFTAEPESRILGEVEETMDIPCRAMGVPLPTLQWYK-DAVPLSKLQ----- 413

  Fly    94 KNQRIGIANSEHKTWTMRIKDIKESDKGWYMCQINTDPMKSQM-GYLDVV-VPPDILDYPTSTDM 156
             |.|..:..|    ..:.|:.:...|.|.:.|..:.:..:.|. .||||. :.|.....|  .|.
Mouse   414 -NPRYKVLPS----GGLHIQKLSPEDSGIFQCFASNEGGEVQTHTYLDVTNIAPAFTQRP--VDT 471

  Fly   157 VVREGSNVTLKCAATGSPEPTITWRRESGVPIELATGE----EVMSIEGTDLVIPNVRRHHMGAY 217
            .|.:|....|:|..:|:|:|.|||:|.:.:   ||:|.    ..|.:|...|.|..|.....|.|
Mouse   472 TVTDGMTAVLRCEVSGAPKPAITWKRGNHI---LASGSVRIPRFMLLESGGLRIAPVFIQDAGNY 533

  Fly   218 LCIASN---GVPPSVSKRI---TLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPK-SINY-W 274
            .|.|:|   .|..|....:   |.:|| ||    :::::  ::|...||.|.:...|: |:.| |
Mouse   534 TCYAANTEASVNASAMLTVWNRTSIVH-PP----EDRVV--IKGTTATLCCGATHDPRTSLRYVW 591

  Fly   275 TRERGEIVPPGGKYSANVTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYRI-- 337
            .::  .:|......|..|.|..|     .|.|:.....:.|.|.|...:..|....|.:|..|  
Mouse   592 KKD--NVVITASSSSRIVVEKDG-----SLVISQTWSGDIGDYTCEIISEGGSDSRTARLEVIEL 649

  Fly   338 --PP 339
              ||
Mouse   650 PHPP 653

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-etaNP_001188701.2 Ig 51..141 CDD:299845 15/90 (17%)
IG_like 51..137 CDD:214653 13/86 (15%)
IG_like 153..237 CDD:214653 28/93 (30%)
Ig 161..224 CDD:299845 23/69 (33%)
IG_like 252..335 CDD:214653 20/84 (24%)
Ig 258..333 CDD:143165 19/76 (25%)
Sdk1NP_808547.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..56
Ig_2 94..169 CDD:290606
IG_like 100..169 CDD:214653
IG_like 183..263 CDD:214653
Ig 197..247 CDD:299845
IG_like 281..357 CDD:214653 1/1 (100%)
IGc2 294..347 CDD:197706
I-set 368..457 CDD:254352 18/99 (18%)
Ig 388..454 CDD:143165 12/76 (16%)
I-set 462..552 CDD:254352 29/94 (31%)
Ig 476..552 CDD:299845 25/78 (32%)
I-set 557..646 CDD:254352 25/102 (25%)
Ig 562..646 CDD:299845 22/96 (23%)
FN3 650..741 CDD:238020 2/4 (50%)
fn3 753..839 CDD:278470
FN3 854..949 CDD:238020
FN3 954..1036 CDD:238020
FN3 1052..1148 CDD:238020
FN3 1158..1253 CDD:238020
FN3 1261..1349 CDD:238020
FN3 1360..1453 CDD:238020
FN3 1459..1554 CDD:238020
FN3 1562..1676 CDD:238020
FN3 1686..1779 CDD:238020
FN3 1784..1865 CDD:238020
FN3 1885..1978 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2057..2080
PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 2187..2193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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