DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-eta and Ncam2

DIOPT Version :9

Sequence 1:NP_001188701.2 Gene:DIP-eta / 33793 FlyBaseID:FBgn0031725 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus


Alignment Length:448 Identity:106/448 - (23%)
Similarity:173/448 - (38%) Gaps:91/448 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 VEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVITKNQR 97
            |.||..:::..|    ..|.||..|.:..|||.........::|.|         ...:|.:|::
  Rat   205 VNVPPAIVMPQK----SFNATAERGEEMTLTCKASGSPDPAISWFR---------NGKLIEENEK 256

  Fly    98 IGIANSEHKTWTMRIKDIKESDKGWYMCQINTDPMKSQ-MGYLDVVVPPDILDYPTSTDMVVREG 161
            ..:..|..:   :.:::|...|.|.|:|:......:.| ..:|.|.|.|.||.....|   ..|.
  Rat   257 YILKGSNTE---LTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNET---TSEN 315

  Fly   162 SNVTLKCAATGSPEPTITWRRE-SGVPIELATGE-------EVMSIEG-TDLVIPNVRRHHMGAY 217
            .:|||.|.|.|.|.|.|||:|. .||  ..:.|:       ||....| :.|.|.:|:....|.|
  Rat   316 GHVTLICEAEGEPVPEITWKRAIDGV--TFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRY 378

  Fly   218 LCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRERGEIV 282
            .|.|::.: ....:.:.|.:.:.|.......:..:.||..:.:.|:.:|.|.:..:|.||:  :|
  Rat   379 DCEAASRI-GGHQRSMHLDIEYAPKFVSNQTMYYSWEGNPINISCDVKANPPASIHWRREK--LV 440

  Fly   283 PPGGKYSANVTEIGGYR--NSMRLHINPLTQAEFGSYRCVAKNSLGD--TDGTIKLYRIP--PNA 341
            .|    :.|.|.:..:.  ..|.|.|.|.:..:||.|.|.|.|.:|.  .:..::|..:|  |..
  Rat   441 LP----AKNTTHLKTHSVGRKMILEIAPTSDNDFGRYNCTATNRIGTRFQEYILELADVPSSPRG 501

  Fly   342 VNYVENFEARHKGKKRTKSSES-----HHPARAQEHSGEDME----------------NP----- 380
            |..:|..:...|.......|..     |:....:|.:.|..:                .|     
  Rat   502 VKIIELSQTTAKISFNKPESHGGVPIHHYQVDVKEVTSETWKIVRSHGVQTTVVLSSLEPNTTYE 566

  Fly   381 -------GKRKAD---------LSLGAESIDSIYGNSAAG-----SRRRQDLGGVLLL 417
                   ||.:.|         |.:...|..||:|..::|     |..:||.||..:|
  Rat   567 VRVAAVNGKGQGDYSKIEIFQTLPVREPSPPSIHGQPSSGKSFKISITKQDDGGAPIL 624

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-etaNP_001188701.2 Ig 51..141 CDD:299845 19/90 (21%)
IG_like 51..137 CDD:214653 18/86 (21%)
IG_like 153..237 CDD:214653 28/92 (30%)
Ig 161..224 CDD:299845 25/71 (35%)
IG_like 252..335 CDD:214653 23/86 (27%)
Ig 258..333 CDD:143165 21/78 (27%)
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452
Ig strand B 38..42 CDD:409452
Ig strand C 50..54 CDD:409452
Ig strand E 76..80 CDD:409452
Ig strand F 90..95 CDD:409452
Ig strand G 104..107 CDD:409452
IGc2 128..189 CDD:197706
Ig strand B 130..139 CDD:409353
Ig strand C 145..153 CDD:409353
Ig strand C' 156..159 CDD:409353
Ig strand D 162..167 CDD:409353
Ig strand E 168..175 CDD:409353
IgI_1_MuSK 209..298 CDD:409562 20/104 (19%)
Ig strand B 228..232 CDD:409562 1/3 (33%)
Ig strand C 241..245 CDD:409562 0/3 (0%)
Ig strand E 264..268 CDD:409562 0/6 (0%)
Ig strand F 278..283 CDD:409562 2/4 (50%)
Ig strand G 291..294 CDD:409562 1/2 (50%)
Ig 300..397 CDD:416386 32/102 (31%)
Ig strand A 300..305 CDD:409353 2/4 (50%)
Ig strand A' 309..313 CDD:409353 1/6 (17%)
Ig strand B 317..325 CDD:409353 4/7 (57%)
Ig strand C 331..337 CDD:409353 3/5 (60%)
Ig strand C' 340..343 CDD:409353 2/4 (50%)
Ig strand D 353..359 CDD:409353 2/5 (40%)
Ig strand E 362..368 CDD:409353 1/5 (20%)
Ig strand F 376..384 CDD:409353 4/7 (57%)
Ig strand G 387..397 CDD:409353 1/9 (11%)
Ig_3 401..479 CDD:404760 22/83 (27%)
Ig strand B 418..422 CDD:409353 0/3 (0%)
Ig strand C 431..435 CDD:409353 0/3 (0%)
Ig strand E 458..462 CDD:409353 2/3 (67%)
Ig strand F 472..477 CDD:409353 2/4 (50%)
Ig strand G 486..489 CDD:409353 0/2 (0%)
FN3 496..588 CDD:238020 13/91 (14%)
fn3 594..678 CDD:394996 11/31 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.000

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