DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and Nectin2

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_033016.3	Gene:	Nectin2 / 19294	MGIID:	97822	Length:	530	Species:	Mus musculus

Alignment Length:	371	Identity:	73/371 - (19%)
Similarity:	134/371 - (36%)	Gaps:	114/371 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 TCALSVILLLILMSQQCYPQRVEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLGP----- 71
            |..|..:|||:|........||.|..||             ...:|....|.|.:  |.|
Mouse    15 TLPLLPLLLLLLQETGAQDVRVRVLPEV-------------RGRLGGTVELPCHL--LPPTTERV 64

  Fly    72 YKVAWLRVDTQTI--------LTIQNHVITKNQRIGI-----ANSEHKTWTMRIKDIKESDKGWY 123
            .:|.|.|:|...:        :...|...:|::...:     .|::.:..|:..:.::..|:|.|
Mouse    65 SQVTWQRLDGTVVAAFHPSFGVDFPNSQFSKDRLSFVRARPETNADLRDATLAFRGLRVEDEGNY 129

  Fly   124 MCQINTDPMKSQMG--YLDVVVPPDILDYPTSTDMVVREGSNVTLKCAATGS-PEPTITW----- 180
            .|:..|.|..::.|  :|.|:..|:  ::..:.::.:...|....:|.:||. |...|||
Mouse   130 TCEFATFPNGTRRGVTWLRVIAQPE--NHAEAQEVTIGPQSVAVARCVSTGGRPPARITWISSLG 192

  Fly   181 -------------------RRESGVPIELATGEEVM------SIEGTDLVIPNVRRHHMGAYLCI 220
                               .|.|.||:..|.|.:|.      |.| ..:::|
Mouse   193 GEAKDTQEPGIQAGTVTIISRYSLVPVGRADGVKVTCRVEHESFE-EPILLP------------- 243

  Fly   221 ASNGVPPSVSKRITLVVHFPPMITV----QNQLIGAVEGKGVTLDCESEAYPKSINY-WTRERGE 280
                        :||.|.:||.:::    .|..:|..|   ..|.|:..:.|:..:| |:
Mouse   244 ------------VTLSVRYPPEVSISGYDDNWYLGRSE---AILTCDVRSNPEPTDYDWS----- 288

  Fly   281 IVPPGGKYSANVTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLG 326
              ...|.:.|:....|.     :|.::.:.:....::.|.|.|::|
Mouse   289 --TTSGVFPASAVAQGS-----QLLVHSVDRMVNTTFICTATNAVG 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	21/109 (19%)
		IG_like	51..137	CDD:214653	19/103 (18%)
		IG_like	153..237	CDD:214653	20/114 (18%)
		Ig	161..224	CDD:299845	18/93 (19%)
		IG_like	252..335	CDD:214653	14/76 (18%)
		Ig	258..333	CDD:143165	13/70 (19%)
Nectin2	NP_033016.3	IG_like	40..149	CDD:214653	23/123 (19%)
		Ig1_PVR_like	48..150	CDD:143195	20/103 (19%)
		Ig	153..248	CDD:299845	21/122 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	382..407
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910