DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-eta and zig-8

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_499714.1	Gene:	zig-8 / 176732	WormBaseID:	WBGene00006985	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	62/264 - (23%)
Similarity:	101/264 - (38%)	Gaps:	58/264 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SNFCQCRKQTCALSVILLLILMS---------QQCYPQ---RVEVPAEVIVDPKFSSPIVNMTAP 55
            ||.|          |||...|.:         ..|..|   |||.|::.||:....:|
Worm     5 SNIC----------VILFSFLYATGHGASEEVMACLRQERSRVENPSQTIVNVVAENP------- 52

  Fly    56 VGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVITKNQRIGIANSEHKTWTMRIKDIKESDK 120
                |:|.|.|.....:::||.||....:||..|...|::.|..::......|.:.::..::.|.
Worm    53 ----AYLHCSVPPDAEHEIAWTRVSDGALLTAGNRTFTRDPRWQVSKKSANIWVLNLRRAEQQDS 113

  Fly   121 GWYMCQINTDPMKSQMGYLDVVVPPDILDYPTSTD------MVVREGSNVTLKCAATGSPEP--- 176
            |.|:|:||.........||.|:.||  |..|:|..      |....|..|.|.|..|.:.:.
Worm   114 GCYLCEINDKHNTVYAVYLKVLEPP--LPSPSSLQKKSTKLMANMSGDEVVLNCTVTSTDKDEEV 176

  Fly   177 -TITWRRESGVPIELATGEEVMSIE---GTDLVIPNVRRHHM---GAYLCIASNGVPPSVSKRIT 234
             .:.|.|:........|.:.::.::   |..:....:|:..|   |.|.|..|       .::.:
Worm   177 LDVVWTRDGNTINFNDTEKYILKVKRDAGVVIETMRIRKATMEDDGNYACEHS-------QQKAS 234

  Fly   235 LVVH 238
            .:||
Worm   235 QIVH 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	22/89 (25%)
		IG_like	51..137	CDD:214653	20/85 (24%)
		IG_like	153..237	CDD:214653	17/99 (17%)
		Ig	161..224	CDD:299845	15/72 (21%)
		IG_like	252..335	CDD:214653
		Ig	258..333	CDD:143165
zig-8	NP_499714.1	IG_like	55..134	CDD:214653	21/78 (27%)
		Ig	55..129	CDD:143165	19/73 (26%)
		ig	158..229	CDD:278476	14/70 (20%)
		IG_like	158..227	CDD:214653	13/68 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810