DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and AgaP_AGAP003235

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_312941.4	Gene:	AgaP_AGAP003235 / 1273907	VectorBaseID:	AGAP003235	Length:	417	Species:	Anopheles gambiae

Alignment Length:	377	Identity:	151/377 - (40%)
Similarity:	221/377 - (58%)	Gaps:	46/377 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 QRVEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVITKN 95
            |..::|.:  ::|:|...|.|:::|.||:|.|||.|::||.|||.|||...||:|.:|..|:|.|
Mosquito     9 QSQQLPVD--LEPEFEGTIQNISSPTGREAILTCSVKNLGRYKVGWLRASDQTVLALQGRVVTHN 71

  Fly    96 QRIGIANSEHKTWTMRIKDIKESDKGWYMCQINTDPMKSQMGYLDVVVPPDILDYPTSTDMVVRE 160
            .||.:.:.:.:||.:||:.::|||:|.||||||..|||.|:|.:||.|||||::..:|.|:.|:|
Mosquito    72 SRISVVHEDFRTWRLRIRQLRESDRGCYMCQINASPMKKQIGCIDVQVPPDIINEESSADIAVQE 136

  Fly   161 GSNVTLKCAATGSPEPTITWRRESG--VPIELATGEEVMSIE---GTDLVIPNVRRHHMGAYLCI 220
            |.:.|:.|.|.|.|.|.:||:||.|  :.:......|::.:|   ||.|.:|.:.|..|||||||
Mosquito   137 GEDATIVCKAVGHPTPRVTWKREDGEYMLLRKPQSRELIRVEAYNGTHLHLPKLERRQMGAYLCI 201

  Fly   221 ASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTR--------- 276
            |||.|||:||||::|.|||.|.:...:||:||..|..|.|:|..||.|..::||.:
Mosquito   202 ASNDVPPAVSKRVSLSVHFAPSVRPTSQLLGAPLGSDVQLECTVEASPMPVSYWLKGGRVLPNSF 266

  Fly   277 -------------ERGEIVPPGGKYSANVTE-IGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGD 327
                         .|.|::..|.||  .:|| ..|:|.:|||.:...:.|:.|:|.||:.||||.
Mosquito   267 AGAANGNYEQPGLSRPEMLLDGPKY--GITEDRHGFRTNMRLVVRSFSPADVGTYHCVSTNSLGR 329

  Fly   328 TDGTIKLY--RIPPNAVNYVEN---------FEARHKGKKRTKS---SESHH 365
            .|||::||  :|.|..|...::         ..||.:|...|.|   :.:||
Mosquito   330 ADGTMRLYEIKIHPGGVQTTDDQLNIIGGLAEAARGRGNSATSSLHPTRTHH 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	45/89 (51%)
		IG_like	51..137	CDD:214653	44/85 (52%)
		IG_like	153..237	CDD:214653	41/88 (47%)
		Ig	161..224	CDD:299845	28/67 (42%)
		IG_like	252..335	CDD:214653	34/105 (32%)
		Ig	258..333	CDD:143165	32/97 (33%)
AgaP_AGAP003235	XP_312941.4	Ig	26..109	CDD:299845	41/82 (50%)
		IG_like	33..119	CDD:214653	45/85 (53%)
		IG_like	129..218	CDD:214653	41/88 (47%)
		Ig	140..206	CDD:299845	28/65 (43%)
		IG_like	233..337	CDD:214653	34/105 (32%)
		IGc2	236..328	CDD:197706	28/93 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D102333at6960
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X97
TreeFam	0	0.000	Not matched by this tool.
	5	4.820