DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and Emb

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_446171.1	Gene:	Emb / 114511	RGDID:	621067	Length:	328	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	55/266 - (20%)
Similarity:	100/266 - (37%)	Gaps:	50/266 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 DMVVREGSNVTLKCAATGSPE---PTITWRRESGVPIELATGEEVMSIEGTDLVIPNVR-----R 211
            ::.:...|::.|:|..|.:.:   ..:||:::..:   |.|.:...:.:..|.:....|     .
  Rat    75 NITLERPSHLELECTFTATEDVMSMNVTWKKDDAL---LETTDGFNTTKMGDTLYSQYRFTVFNS 136

  Fly   212 HHMGAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESE-AYPKSINY-W 274
            ..||.|.|.....:..:.:.|:       |.:..:|:.:....|....|.||.: ..|  :|: |
  Rat   137 KQMGKYSCFLGEELRGTFNIRV-------PKVHGKNKPLITYVGDSTVLKCECQNCLP--LNWTW 192

  Fly   275 TRERGEIVPP-----GGKYSANVTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKL 334
            ....|....|     ..|:..|    |.|.|..:|.:..|.:.:.|||.|.|...||:::..|||
  Rat   193 YMSNGTAQVPIDVHVNDKFDIN----GSYANETKLKVKHLLEEDGGSYWCRAAFPLGESEEHIKL 253

  Fly   335 ----YRIPPN-----------AVNYVENFEARHKGKKRT----KSSESHHPARAQEHSGEDMENP 380
                :.:|..           .|..:...|...:.||..    |..|.....::.:.:|.:...|
  Rat   254 VVLSFMVPLKPFLAIIAEVILLVAIILLCEVYTQKKKNDPDDGKEFEQIEQLKSDDSNGIENNVP 318

  Fly   381 GKRKAD 386
            ..||.|
  Rat   319 RYRKTD 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845
		IG_like	51..137	CDD:214653
		IG_like	153..237	CDD:214653	15/89 (17%)
		Ig	161..224	CDD:299845	14/70 (20%)
		IG_like	252..335	CDD:214653	26/93 (28%)
		Ig	258..333	CDD:143165	22/81 (27%)
Emb	NP_446171.1	I-set	84..144	CDD:254352	12/62 (19%)
		IG_like	172..255	CDD:214653	26/88 (30%)
		Ig	177..252	CDD:143165	22/80 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..328		9/36 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910