DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and ncam1b

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_005157462.1	Gene:	ncam1b / 114442	ZFINID:	ZDB-GENE-010822-2	Length:	1055	Species:	Danio rerio

Alignment Length:	328	Identity:	84/328 - (25%)
Similarity:	134/328 - (40%)	Gaps:	63/328 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 VEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVITKNQR 97
            ::|...|:...:......|.||.:|....|.|.........|.|.|         .|..:....:
Zfish   201 IKVVVNVLPTIRIRQAETNATADMGFSTLLACDPDGFPEPIVTWRR---------NNAPLESGNK 256

  Fly    98 IGIANSEHKTWTMRIKDIKESDKGWYMCQINTDPMKSQMGY-LDVVVPPDI--LDYPTSTDMVVR 159
            ........:   |.:.|:.:.|:|.|.|.......:|:... |.|.|.|.|  |:..|:|:|
Zfish   257 YSFNEDGSE---MTVLDVTKLDEGDYTCIAKNKAGESEQELSLKVFVQPKITYLESQTTTEM--- 315

  Fly   160 EGSNVTLKCAATGSPEPTITW----------RRESGVPIELAT---GEEVMSIEGTDLVIPNVRR 211
             ...|||.|.|||.|.|||||          .:|....|..|:   .|:....:|..||..:.|.
Zfish   316 -DEQVTLTCEATGDPTPTITWSFGTRVFTEGEQEQQKRIYQASWTRPEQHKGPDGEVLVRSDARV 379

  Fly   212 HHM----------GAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAV-----EGKGVTLD 261
            ..:          |.|||.|.|.:..:| :.::|.|.:.|      :::|:|     ||....:.
Zfish   380 SSLTLKYPQYTDAGQYLCTARNAIGETV-QPVSLEVRYAP------KILGSVAVYTWEGNPANIS 437

  Fly   262 CESEAYPKSINY-WTRERGEIVPPGGKYSANVTEIGGYR--NSMRLHINPLTQAEFGSYRCVAKN 323
            ||..|:|..::. |.|: |..:|     :||.:.|..:.  ::..|.:||.:|::||:|.|...|
Zfish   438 CEVLAHPSDVSITWLRD-GFQLP-----NANTSNIKIHNTPSASYLEVNPESQSDFGNYNCTTSN 496

  Fly   324 SLG 326
            .:|
Zfish   497 EIG 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	18/90 (20%)
		IG_like	51..137	CDD:214653	17/85 (20%)
		IG_like	153..237	CDD:214653	31/106 (29%)
		Ig	161..224	CDD:299845	26/85 (31%)
		IG_like	252..335	CDD:214653	24/83 (29%)
		Ig	258..333	CDD:143165	21/72 (29%)
ncam1b	XP_005157462.1	Ig	20..112	CDD:299845
		I-set	21..111	CDD:254352
		IG_like	121..205	CDD:214653	1/3 (33%)
		IGc2	128..189	CDD:197706
		Ig	208..301	CDD:299845	19/104 (18%)
		I-set	212..298	CDD:254352	18/97 (19%)
		I-set	298..414	CDD:254352	37/120 (31%)
		Ig	300..414	CDD:299845	36/118 (31%)
		IG_like	426..505	CDD:214653	23/80 (29%)
		Ig	434..505	CDD:143165	21/72 (29%)
		FN3	513..606	CDD:238020
		FN3	629..720	CDD:238020
		Chorion_3	<815..1019	CDD:253174
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100