DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-eta and ntm

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	413	Identity:	116/413 - (28%)
Similarity:	185/413 - (44%)	Gaps:	79/413 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 MSQQCYPQRVEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQ 88
            |:..|..|.|.|.:.   |..|...:.|:|...|..|.|.|.| |....:||||  :..|||...
Frog    21 MAVLCLLQGVPVRSG---DAGFPKAMDNVTVRQGDSAILRCTV-DNRVTRVAWL--NRSTILYTG 79

  Fly    89 NHVITKNQRIGIANSEHKTWTMRIKDIKESDKGWYMCQINTD--PMKSQMGYLDVVVPPDILDYP 151
            |...:.:.|:.:..:....:::.|:::...|:|.|.|.:.||  |..|:: :|.|.|||.|:|
Frog    80 NDKWSIDPRVVLLANTKSQYSIEIQNVDIYDEGPYTCSVQTDNHPKTSRV-HLIVQVPPRIVD-- 141

  Fly   152 TSTDMVVREGSNVTLKCAATGSPEPTITWRRESGVPIELATGEEVMSIEGTDLVIPNVRRHHMGA 216
            .|:.:.|.|||||:|.|.|.|.|||.:.||..|.......:.:|.:.|.|       :.|...|.
Frog   142 ISSSIAVNEGSNVSLICIANGRPEPVVNWRYLSPKARGFVSEDEYLEITG-------ITREQSGI 199

  Fly   217 YLCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRE---- 277
            |.|.|||.|.....:|:.|.|::||.| :..|.|||..|....|.||:.|.|.:..:|.:|
Frog   200 YECSASNDVSAPDVRRVKLTVNYPPYI-LDAQNIGAPLGHRGILQCEASAVPAADFFWYKEDKRL 263

  Fly   278 ----RGEIVPPGGKYSANVTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYRIP 338
                ||             .::.......|:....:::.::|:|.|:|||.||.::.:|.|:
Frog   264 SDSWRG-------------VKVENRETISRVTFLNVSEQDYGNYTCMAKNLLGHSNASIILF--- 312

  Fly   339 PNAVNYVENFEARHKGKKRTKSSESHHPARAQEHSGEDMENPGKRKADLSLGAESIDSIY-GNSA 402
                   |.|::......:.:|:.:..|          ::.||              ::: |||
Frog   313 -------ELFQSTSSPLLQEESTAALTP----------LKGPG--------------AVHDGNS- 345

  Fly   403 AGSRRRQDLGG--VLLLLLPVAV 423
             ||.:......  :||||||.::
Frog   346 -GSTQCSFCAPLLILLLLLPFSL 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	27/91 (30%)
		IG_like	51..137	CDD:214653	26/87 (30%)
		IG_like	153..237	CDD:214653	30/83 (36%)
		Ig	161..224	CDD:299845	23/62 (37%)
		IG_like	252..335	CDD:214653	21/90 (23%)
		Ig	258..333	CDD:143165	18/82 (22%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	27/91 (30%)
		IG_like	45..133	CDD:214653	27/91 (30%)
		IG_like	143..220	CDD:214653	30/83 (36%)
		IGc2	150..209	CDD:197706	25/65 (38%)
		ig	227..311	CDD:278476	24/96 (25%)
		IG_like	230..311	CDD:214653	24/93 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm47726
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060