DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-eta and si:ch211-222f23.6

DIOPT Version :9

Sequence 1:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001120876.1	Gene:	si:ch211-222f23.6 / 100141493	ZFINID:	ZDB-GENE-070912-208	Length:	367	Species:	Danio rerio

Alignment Length:	331	Identity:	70/331 - (21%)
Similarity:	107/331 - (32%)	Gaps:	92/331 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 NMTAPVGRDAFLTCVVQDL-----GPYKVAWLRVDTQTILTIQNH------VITKNQRIG----- 99
            |....:|.||.|.|   ||     ...:|.|.:      .|.:||      :|.|:.|..
Zfish    31 NKAVMIGEDATLFC---DLTATQENTSRVVWQK------QTSENHQPETFFIIHKDGRTEHRDLQ 86

  Fly   100 -----IANSEHKTWTMRIKDIKESDKGWYMCQINTDPMKSQMGYLDVVVPPDILDYPTSTDMVVR 159
                 :.|......::::..:|..|.|.|.|....:..::|......|:.|.:.....||.  |.
Zfish    87 DHVRFVGNLMENNGSIQLMGLKLVDDGIYTCIFTINEQQAQKVISVTVLVPPVGSVMGSTH--VS 149

  Fly   160 EGSNVTL-KCAATGS-PEPTITWRRESGVPIELATGEEVMSIEGTDLVIPNVRRHHMGAYLCIAS 222
            ...:|.| .|.|:|: |...:.||               :....|.|........|......:.|
Zfish   150 GAFSVDLASCMASGARPAARVFWR---------------LGALNTSLNTHTSSTEHSDGTFTVQS 199

  Fly   223 N--GVPPS---------VSKRITLV----------VHFPPMITV-----QNQLIGAVEGKGVTLD 261
            :  |||..         |.:.||..          ||:||.:.:     .|....|.|     ..
Zfish   200 HIYGVPSKHLHQKKIQCVVQHITFTEDLELEYQINVHYPPDLVIISPDDPNNPAEAEE-----YH 259

  Fly   262 CESEAYPKSINYWTRERGEIVPPGGKYSANVTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLG 326
            ||.:..|.....|.| ..|......:|..|...:.  ::|:.|:         |.|.|.|.|..|
Zfish   260 CEVDCNPTPTYIWKR-MNESEGRAPRYEGNKLFLP--KSSVDLN---------GVYICTASNQYG 312

  Fly   327 DTDGTI 332
            ...|::
Zfish   313 SASGSV 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	23/110 (21%)
		IG_like	51..137	CDD:214653	23/106 (22%)
		IG_like	153..237	CDD:214653	21/106 (20%)
		Ig	161..224	CDD:299845	12/66 (18%)
		IG_like	252..335	CDD:214653	19/81 (23%)
		Ig	258..333	CDD:143165	17/75 (23%)
si:ch211-222f23.6	NP_001120876.1	V-set	34..135	CDD:284989	22/109 (20%)
		IG_like	34..134	CDD:214653	22/108 (20%)
		Ig	138..235	CDD:299845	21/113 (19%)
		Ig	257..317	CDD:299845	17/76 (22%)
		IG_like	259..321	CDD:214653	17/72 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910