Protein Alignment GluRIIB and Ir75b

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 133/642 - (20%)
• Similarity: 236/642 - (36%)
• Gaps: 162/642 - (25%)

  Fly   276 PVHDEIDVFDNSVDTRFSSLGSQLVYDSIVLFYNALLEIS-QRPGFYIPNFSCGRGFWQPGPRLV 339
            |:|.:|.:.|:.::.....||             ..|:|: .:.|..:...|..|.|......|:
  Fly    46 PLHSDIQLNDDFLNHNILKLG-------------VFLDINCDKSGTVLDMASAKRFFSHRYHWLI 97

  Fly   340 EQMKQITPKMVKPPFKTQRLQINADGQREDFNLEVYNPIIDRVTH-IWNKEFQLVD-FEKLRE-- 400
            .. :.:...:::..||..::.::||              :..||| .::|.|.|.| :.|.|:
  Fly    98 YD-RSMNFSVLESHFKEAQIFVDAD--------------VTYVTHDPFSKNFLLYDVYNKGRQLG 147

  Fly   401 -------------NST---------QALKQKRLQNKEDFSQKPIRYT-VATRVG-----KPYFSW 437
                         |.|         :...:..||:::.|:...:|.| |.|.:.     |..|.:
  Fly   148 GELNITADREIFCNKTNCRVERYLSELYTRSALQHRKSFTGLTMRATAVVTALPLNVSIKEIFDF 212

  Fly   438 REEPEGVHYEGNERFEGYAV-----DLIYMLAQECKFDFNFEPVRDNKYGSYDANTDEWDGIIRQ 497
            ......:..:...|. ||..     |::     :|||.:.|.              |.|.
  Fly   213 MNSKYRIQLDTYARL-GYQARQPLRDML-----DCKFKYIFR--------------DRWS----- 252

  Fly   498 LIDNNAQIG-ICDLTITQARRSVVDFTVPFMQLGISILSYKEPPPKADIY--------------- 546
              |.||..| |.||.:.:|..::..|...|.:     ..:.:|..|..::
  Fly   253 --DGNATGGMIGDLILDKADLAIAPFIYSFDR-----ALFLQPITKFSVFREICMFRNPRSVSAG 310

  Fly   547 ----AFLNPYNAEVWLFVMIAMMITAFALIFTGRIDQYEWDQPVENVNREMERQNIW--HLSNAL 605
                .||.|::..|||...:.:::....|          |      |...:||:..|  .|..:.
  Fly   311 LSATEFLQPFSGGVWLTFALLLLLAGCLL----------W------VTFILERRKQWKPSLLTSC 359

  Fly   606 WLVLGSMLNQGCDLLPRGLPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAG-----DIGSLH 665
            .|..|:...||..|.||.:..|:  ||   |||:::...:......|..||:.|     :|.:|.
  Fly   360 LLSFGAGCIQGAWLTPRSMGGRM--AF---FALMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQ 419

  Fly   666 DLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAW-NKMLSFK--PDAFTKNNEEGVDRVKLSKGT 727
            .|.|.| :..|......|.:|...|.:.|.|..: .|:|..|  ||......|.||..|:..:|
  Fly   420 QLADSN-LDVGIEPTVYTRIYVETSEEPDVRDLYRKKVLGSKRSPDKIWIPTEAGVLSVRDQEG- 482

  Fly   728 YAFLMETTNLQYYVQRN------CELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGEL 786
            :.::........:|:::      |||.:| ......|....:...:.:...:.:..||:.|.|..
  Fly   483 FVYITGVATGYEFVRKHFLAHQICELNEI-PLRDASHTHTVLAKRSPYAELIKLSELRMLETGVH 546

  Fly   787 FKLRNKWFNSNESTCDSNVPTIDDGQFDMDSVGGLFVVLIVGVVVGLVIGVAEFLWH 843
            ||....|..: :..|..:..|:..|   ::....||::|:..:::.:.|...|.:||
  Fly   547 FKHERSWMET-KLHCYQHNHTVAVG---LEYAAPLFIILLGAIILCMGILGLEVIWH 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	22/118 (19%)
		ANF_receptor	41..378	CDD:279440	17/102 (17%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	92/419 (22%)
		Lig_chan	555..822	CDD:278489	64/282 (23%)
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	75/328 (23%)
		Lig_chan	343..585	CDD:278489	61/253 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462584
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740