Protein Alignment GluRIIB and GLR2.1

DIOPT Version :10

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_198062.2
• Gene: GLR2.1 / 832768
• AraportID: AT5G27100
• Length: 901
• Species: Arabidopsis thaliana
• Alignment Length: 938
• Identity: 189/938 - (20%)
• Similarity: 359/938 - (38%)
• Gaps: 202/938 - (21%)

  Fly     4 LQFLVLLALAIASGANEDT-----LVIKIGAIFFD-----TEMKLADAFSAALEEVNAINPALKL 58
            |.|:::..:.:....|..|     :|..||..:.:     ..|.|:|.:|:        :|..:.
plant    12 LFFVIVFLMQVGEAQNRITNVNVGIVNDIGTAYSNMTLLCINMSLSDFYSS--------HPETQT 68

  Fly    59 DAIKRYV-TVDDSIVLQDISCDLI-GSGVAAIFGPSSKTNSDIVEVLCNMTGIPHLQFDWHPQQS 121
            ..:...| :.:|.:.....:.||| ...|.||.||.:...:..:..:...:.:|.:.:
plant    69 RLVTTVVDSKNDVVTAAAAALDLITNKEVKAILGPWTSMQAQFMIEMGQKSQVPIVTY------- 126

  Fly   122 NRERMNHQLTVNVAPMELFLSAAFSDILASKTFDWKSFTIAYERSSHLIRLQHIL---AWKQLHK 183
                                 :|.|..|||....: .|...|:.||.:..::.|:   .|:::..
plant   127 ---------------------SATSPSLASIRSQY-FFRATYDDSSQVHAIKEIIKLFGWREVAP 169

  Fly   184 A--------GIK------MQEFERGDDYRILWKRI--NNAREKFV------LLDCPSDI----LV 222
            .        ||.      :||.    :.||.::.:  .||.:..:      ::..|:.:    ||
plant   170 VYVDDTFGEGIMPRLTDVLQEI----NVRIPYRTVISPNATDDEISVELLRMMTLPTRVFVVHLV 230

  Fly   223 DVINA-------SIGYNMTGSFNHLFLTNLDTHLSGIDGFYSRDFTVAVAAVRIRTYVPPPVHDE 280
            :::.:       .||....|..  ..|||..|.:..|  ....:.......:.::||||.  ..|
plant   231 ELLASRFFAKATEIGLMKQGYV--WILTNTITDVLSI--MNETEIETMQGVLGVKTYVPR--SKE 289

  Fly   281 IDVFDNSVDTRF--SSLG--SQLVYDSIVLFYNALLEISQRPGFYIP-----NFS--CGRGFWQP 334
            ::.|.:....||  |.|.  ....||:......|:.|.......::.     |.|  .|.|..|.
plant   290 LENFRSRWTKRFPISDLNVYGLWAYDATTALALAIEEAGTSNLTFVKMDAKRNVSELQGLGVSQY 354

  Fly   335 GPRLVEQMKQITPKMVKPPFKTQRLQINADGQREDFNLEVYNPIIDRVTHIWNKEFQL---VDFE 396
            ||:|::.:.::..:.:...|:.    ||.:.|...|.:...|....|....|.||:.|   || :
plant   355 GPKLLQTLSRVRFQGLAGDFQF----INGELQPSVFEIVNVNGQGGRTIGFWMKEYGLFKNVD-Q 414

  Fly   397 KLRENSTQALKQKRLQN---KEDFSQKPIRYTVAT-----RVGKP-------YFSWREEPEGVHY 446
            |....:|.:..|.||:.   ..|.:..|..:.:.|     ::|.|       :.....:|    .
plant   415 KPASKTTFSSWQDRLRPIIWPGDTTSVPKGWEIPTNGKRLQIGVPVNNTFQQFVKATRDP----I 475

  Fly   447 EGNERFEGYAVDLIYMLAQECKFD--FNFEPVRDNKYGSYDANTDEWDGIIRQLIDNNAQIGICD 509
            ..:..|.|:::|....:.|...:|  ::|.|.:|   |.|||       ::.|:........:.|
plant   476 TNSTIFSGFSIDYFEAVIQAIPYDISYDFIPFQD---GGYDA-------LVYQVYLGKYDAVVAD 530

  Fly   510 LTITQARRSVVDFTVPFMQLGISILSYKEPPPKADIYAFLNPYNAEVWLFVMIAMMITAFALIFT 574
            .||:..|...|||::|:...|:.::...:...:.....||.|....:||..:::..|....:
plant   531 TTISSNRSMYVDFSLPYTPSGVGLVVPVKDSVRRSSTIFLMPLTLALWLISLLSFFIIGLVV--- 592

  Fly   575 GRIDQYEWDQPVEN-VNREMERQNIWHLSNALWLVLGSMLNQGCDLLPRGLPM----RLLTAFWW 634
                   |  .:|: ||.:.:....:.||...|.....|:     ..||...:    |::...|:
plant   593 -------W--VLEHRVNPDFDGPGQYQLSTIFWFSFSIMV-----FAPRERVLSFWARVVVIIWY 643

  Fly   635 IFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQNK---VQFGTIRGGATSVYFSESNDTDNR 696
            ...|:::|:|.|.||:.:|:..:...:.:::.|:.:.:   .|...|.|......|||::
plant   644 FLVLVLTQSYTASLASLLTTQHLHPTVTNINSLLAKGESVGYQSSFILGRLRDSGFSEAS----- 703

  Fly   697 MAWNKMLSF-KPD----AFTKNNEEGVDRVKLSKGTYAFLMETTNLQYYVQRNC-ELTQIGESFG 755
                 ::|: .|:    ..:|...||        |..|.|||...::.::.:.| :...:...|.
plant   704 -----LVSYGSPEHCDALLSKGQAEG--------GVSAVLMEVPYVRIFLGQYCNKYKMVQTPFK 755

  Fly   756 EKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNKWFNSNESTC-------DSNVPTIDDGQF 813
            ....|...|:.:...:::|..||::.|..:..:|.|.||...:.:|       |.| |::...|.
plant   756 VDGLGFVFPIGSPLVADISRAILKVEESNKANQLENAWFKPIDESCPDPLTNPDPN-PSVSFRQL 819

  Fly   814 DMDSVGGLFVVLIVGVVVGLVIGVAEFL 841
            ..||...||:|..:...:.|:..|.:||
plant   820 GFDSFWVLFLVAAIVCTMALLKFVYQFL 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..387	CDD:380605	77/414 (19%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	79/400 (20%)
GLR2.1	NP_198062.2	PBP1_GABAb_receptor_plant	33..411	CDD:380645	82/428 (19%)
		GluR_Plant	452..794	CDD:270404	77/390 (20%)
		Lig_chan	574..833	CDD:459656	61/294 (21%)