Protein Alignment GluRIIB and GLR2.6

DIOPT Version :10

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001330285.1
• Gene: GLR2.6 / 830988
• AraportID: AT5G11180
• Length: 967
• Species: Arabidopsis thaliana
• Alignment Length: 976
• Identity: 187/976 - (19%)
• Similarity: 341/976 - (34%)
• Gaps: 305/976 - (31%)

  Fly     4 LQFLVLLALAIASGANEDTLVIKIGAIFFDTEMKLADAFSAALEEVNAINPALK-----LDAIKR 63
            :.|||||     ..:.::.|.:::| |..||...|     ||| .:.|||.:|.     .:..|.
plant    20 INFLVLL-----GKSQQEVLQVQVG-IVLDTNATL-----AAL-SLRAINMSLSEFYNTHNGFKT 72

  Fly    64 YVTVDDSIVLQDISCDLIGSG-----------VAAIFGPSSKTNSDIVEVLCNMTGIPHLQFDWH 117
            .:.::    ::|....::|:.           |.||.||.:...:..:..|.|.:.:|.:.|
plant    73 RIVLN----IRDSKRTVVGAAASALYLIKKREVVAIIGPGNSMQAPFLINLGNQSQVPIISF--- 130

  Fly   118 PQQSNRERMNHQLTVNVAPMELFLSAAFSDILASKTFDWKSFTIAYERSSHLIRLQHILAWKQLH 182
                                     :|.|.:|.|.            ||.:.||..|..: .|:|
plant   131 -------------------------SASSPVLDSL------------RSPYFIRATHDDS-SQVH 157

  Fly   183 KAGIKMQEFERGDDYRILWKRI------NNAREKFV--LLDCPSDILV--------------DVI 225
            .....::.|.        |:.:      |...|..:  |:|...:|.|              |::
plant   158 AISAIIESFR--------WREVVPIYADNEFGEGILPYLVDAFQEINVRIRYRSAISVHSTDDLV 214

  Fly   226 NASIGYNMTGSFNHLFLTNLDTHLSGIDGFYSRDFTVA-VAAVRIRTY---VPPPVHDEIDVF-D 285
            ...: |.:......:|:.::...|.      ||.|::| ...:..:.|   |...:.|::.|. :
plant   215 KKEL-YKLMTMPTRVFIVHMLPDLG------SRLFSIAKEIGMMTKGYVWIVTNGIADQMSVMGE 272

  Fly   286 NSVDTRFSSLGSQLVYD-SIVLFYNALLEISQRPGF---YIPNFSC------------------- 327
            :|::.....||.:..:. |..|.|   ||...|..|   .:.||.|
plant   273 SSLENMHGVLGVKTYFSRSKELMY---LETRWRKRFGGEELNNFECWGYDTATALAMSIEEISSN 334

  Fly   328 ----------------------GRGFWQPGPRLVEQMKQITPKMVKPPFKTQRLQINADGQREDF 370
                                  ...|...||:|::.:..::.|.|...|:.:      :|:.|..
plant   335 VNMSFSQTKRNTSRDDTGTDLDDLSFALSGPKLLQALATVSFKGVAGRFQLK------NGKLEAT 393

  Fly   371 NLEVYN--PIIDRVTHIWNKEFQLVDFEKLRENSTQALKQKRLQNKEDFSQKPIRYTVATRVGKP 433
            ..::.|  ...:|....|..:..||  :.||.|.| .:|.....::    .:||.:.     |..
plant   394 TFKIVNIEESGERTVGFWKSKVGLV--KSLRVNQT-GIKISHSSHR----LRPIIWP-----GDT 446

  Fly   434 YFSWREEPEGVHYEGNER----------------------------FEGYAVDLIYMLAQECKFD 470
            .|    .|:|..:..|.:                            ..|:.:|:.....::..:.
plant   447 IF----VPKGWEFPTNAKKLRIAVPKKDGFNNFVEVTKDANTNAPTITGFCIDVFDTAMRQMPYA 507

  Fly   471 FNFEPV----RDNK-YGSYDANT-----DEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVP 525
            ..:|.:    .|.| .||||...     .|:||            .:.|.||...|.:.|||.:|
plant   508 VPYEYIPFETPDGKPRGSYDEMVYHVFLGEFDG------------AVGDTTILANRSTYVDFALP 560

  Fly   526 FMQLGISILSYKEPPPKADIYAFLNPYNAEVWL-----FVMIAMMITAFALIFTGRIDQYEWDQP 585
            :.:.||.::...:...:...:.||.|...|:|.     |:.|.:|:..|         :|:
plant   561 YSETGIVVVVPVKDEREKGKWVFLKPLTRELWFLTAASFLYIGIMVWIF---------EYQ---- 612

  Fly   586 VENVNREMERQNIWH-LSNALWLVLGSMLNQGCDLLP-RGLPMRLLTAFWWIFALLISQTYIAKL 648
               .:.:..:|:|.: :||..:....::.  ...:.| ..:..|:|...|....|:::|:|.|.|
plant   613 ---ASGDFRKQSIINKISNVFYFSFSTLF--FAHMRPSESIFTRVLVVVWCFVLLILTQSYTATL 672

  Fly   649 AAFITSSKIAGDIGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKP------ 707
            .:.:|..::...:..:.||           |....::.:...:.|..|:   |.:.:|.
plant   673 TSMLTVQELRPTVRHMDDL-----------RNSGVNIGYQTGSFTFERL---KQMGYKESRLKTY 723

  Fly   708 -------DAFTKNNEEGVDRVKLSKGTYAFLMETTNLQYYVQRNC-ELTQIGESFGEKHYGIAVP 764
                   :.|.|.:..|        |..|...|...::.::.:.| :.|.|..:|....:|.|.|
plant   724 DTPQEMHELFLKKSSNG--------GIDAAFDEVAYVKLFMAKYCSKYTIIEPTFKADGFGFAFP 780

  Fly   765 LNADFRSNLSVGILRLSERGELFK-LRNKWFNSNESTCDSNVPTIDDGQFDMD--SVGGLFVVLI 826
            |.:....:||..||.::| ||..| :.|||....:...||   |..|....:|  |...||.::.
plant   781 LGSPLVPDLSRQILNITE-GETMKAIENKWLLGEKHCLDS---TTSDSPIRLDHHSFEALFTIVF 841

  Fly   827 V 827
            |
plant   842 V 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..387	CDD:380605	79/450 (18%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	84/432 (19%)
GLR2.6	NP_001330285.1	PBP1_GABAb_receptor_plant	38..421	CDD:380645	82/460 (18%)
		GluR_Plant	460..810	CDD:270404	77/402 (19%)
		Lig_chan	590..842	CDD:459656	61/295 (21%)