Protein Alignment GluRIIB and GLR3.6

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001326369.1
• Gene: GLR3.6 / 824311
• AraportID: AT3G51480
• Length: 903
• Species: Arabidopsis thaliana
• Alignment Length: 965
• Identity: 192/965 - (19%)
• Similarity: 333/965 - (34%)
• Gaps: 310/965 - (32%)

  Fly    24 VIKIGAIFFDTEM---KLADAFSAALEEVNAINPALKLDAIKRYVTVDDSIVLQDIS-------- 77
            |:.||::|....:   .:..|..||:|:|||....|....::        |::.|..
plant    29 VVNIGSVFTFNSLIGKVIKVAMDAAVEDVNASPSILNTTTLR--------IIMHDTKYNGFMSIM 85

  Fly    78 --CDLIGSGVAAIFGPSSKTNSDIVEVLCNMTGIPHLQFD-WHPQQSNRERMNHQLTVNVAPMEL 139
              ...:.|...||.||...|.:.:|..:.....||.|.|. ..|..|   .:.....:..:..:|
plant    86 EPLQFMESETVAIIGPQRSTTARVVAHVATELKIPILSFSATDPTMS---PLQFPFFIRTSQNDL 147

  Fly   140 FLSAAFSDILASKTFDWKSFTIAYERSSHLIRLQHILAWKQLHKAGIKMQEFERGDD------YR 198
            |..||.:||:  :.:.|:.....|                              |||      ..
plant   148 FQMAAIADIV--QFYGWREVVAIY------------------------------GDDDYGRNGVA 180

  Fly   199 ILWKRINNAR----EKFVLLDCP-----SDILVD---------VINAS-------------IGYN 232
            .|..|::..|    .|..|...|     :|:|:.         |::||             :|..
plant   181 ALGDRLSEKRCRISYKAALPPAPTRENITDLLIKVALSESRIIVVHASFIWGLELFNVARNLGMM 245

  Fly   233 MTGSFNHLFL-TN-------------LDTHLSGIDGFYSRDFTVAVAAVRIRTYVPPPVHDE--I 281
            .||   :::: ||             ||| ::.|.|           .:.:|.:.|..:..:  :
plant   246 STG---YVWIATNWLSTIIDTDSPLPLDT-INNIQG-----------VITLRLHTPNSIMKQNFV 295

  Fly   282 DVFDNSVDTRFSSLGSQLVYDSIVLFYNALLEISQRPGFYIPNFSCGRG---------------- 330
            ..:.|......|:. :...||::.|...|:.:..::.|    |.|..:.
plant   296 QRWHNLTHVGLSTY-ALYAYDTVWLLAQAIDDFFKKGG----NVSFSKNPIISELGGGNLHLDAL 355

  Fly   331 -FWQPGPRLVEQMKQITPKMVKPPFKTQRLQINADGQRE---DFNLEVYNPIIDRVTHIWNKEFQ 391
             .:..|...:|.:.|:.             :|...|:.:   |.||  .||..| |.::....:.
plant   356 KVFDGGKIFLESILQVD-------------RIGLTGRMKFTSDRNL--VNPAFD-VLNVIGTGYT 404

  Fly   392 LVDFEKLRENSTQALKQKRLQNKEDFSQK-------------PIRYTVAT-----RVGKPYFSWR 438
            .:.: ....:....:....::|.....||             |..:..:.     |:|.|. .:|
plant   405 TIGY-WFNHSGLSVMPADEMENTSFSGQKLHSVVWPGHSIKIPRGWVFSNNGRHLRIGVPN-RYR 467

  Fly   439 EEPEGVHYEGNERFEGYAVDL----IYMLAQECKFDF-----------NFEPVRDNKYGSYDANT 488
            .| |.|..:.|....|:.||:    |.:|.....|:.           |.|.||....|.|||
plant   468 FE-EVVSVKSNGMITGFCVDVFIAAINLLPYAVPFELVAFGNGHDNPSNSELVRLITTGVYDA-- 529

  Fly   489 DEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPPPK--ADIYAFLNP 551
                             |:.|:||...|..:.|||.|:::.|:.:::   |..|  :...|||.|
plant   530 -----------------GVGDITIITERTKMADFTQPYVESGLVVVA---PVRKLGSSAMAFLRP 574

  Fly   552 YNAEVWLFVMIAMMITAFALIFTGRIDQYEWDQPVENVNREMERQNIW---HLSNALWLVLGSML 613
            :..::||       |.|.:.:..|.:                    ||   |..|..:
plant   575 FTPQMWL-------IAAASFLIVGAV--------------------IWCLEHKHNDEF------- 605

  Fly   614 NQGCDLLPRGLPMR-LLTAFW-------------------------WIF-ALLISQTYIAKLAAF 651
                    ||.|.| ::|.||                         |:| .|:|:.:|.|.|.:.
plant   606 --------RGPPRRQVITTFWFSFSTLFFSHRETTTSNLGRIVLIIWLFVVLIINSSYTASLTSI 662

  Fly   652 ITSSKIAGDIGSLHDLVDQNKVQFGTIRGGATSVY-FSESNDTDNRMAWNKMLSFKPDAFTKNNE 715
            :|..:::..|..:..| ..|....|..:|.....| ..|.|...:|:...:    .|:.:.|...
plant   663 LTVHQLSSPIKGIETL-QTNHDPIGYPQGSFVRDYLIHELNIHVSRLVPLR----SPEEYDKALR 722

  Fly   716 EGVDRVKLSKGTYAFLMETTNLQYYVQRNCELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRL 780
            :|..:    .|..|.:.|...::.::...||...:|:.|.:..:|.|.|.|:....::|..||:|
plant   723 DGPGK----GGVAAVVDERAYIELFLSNRCEFGIVGQEFTKNGWGFAFPRNSPLAVDVSAAILQL 783

  Fly   781 SERGELFKLRNKWFNSNESTCDSNVPTIDDGQFDMDSVGGLFVVLIVGVVVGLVI 835
            ||.|::.::|:||.  ....|......|:..:.::.|..|||||..|..|:.|.:
plant   784 SENGDMQRIRDKWL--LRKACSLQGAEIEVDRLELKSFWGLFVVCGVACVLALAV 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	81/453 (18%)
		ANF_receptor	41..378	CDD:279440	75/420 (18%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	95/425 (22%)
		Lig_chan	555..822	CDD:278489	61/297 (21%)
GLR3.6	NP_001326369.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.870