Protein Alignment GluRIIB and GLR2.9

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001325277.1
• Gene: GLR2.9 / 817458
• AraportID: AT2G29100
• Length: 942
• Species: Arabidopsis thaliana
• Alignment Length: 1017
• Identity: 208/1017 - (20%)
• Similarity: 381/1017 - (37%)
• Gaps: 223/1017 - (21%)

  Fly     4 LQFLV--LLALAIASGANEDTLVIKIGAIFFDTEMKLADAFS--------AALEEVNAINPALKL 58
            |.:.|  .|.:.:..|.|: |..||:|.:     :.|...||        .|:.:..|.:|
plant    10 LSYFVCGFLLMGVGLGQNQ-TSEIKVGVV-----LDLNTTFSKICLTSIKMAVSDFYADHP---- 64

  Fly    59 DAIKRYVT---------VDDSIVLQDISCDLIGS-GVAAIFGPSSKTNSDIVEVLCNMTGIPHLQ 113
                .|:|         ::|::.....:.|||.: .|:||.||.:...:|.:..|.|.|.:|.:.
plant    65 ----NYLTRLTLHVRDSMEDTVQASAAALDLIKTEQVSAIIGPINSMQADFMIKLANKTQVPTIT 125

  Fly   114 FDWHPQQSNRERMNHQLTVNVAPMELFLSAAFSD-----ILAS--KTFDWKSFTIAYERSSHLIR 171
            |         ...:..||...:|  .|:.|...|     .:||  |.|.|:.....|..:.....
plant   126 F---------SATSPLLTSIKSP--YFVRATIDDSSQVRAIASIFKFFRWRRVVAIYVDNEFGEG 179

  Fly   172 LQHILAWKQLHKAGIKMQEF--ERGDD-----YRILWKRINNAREKFVLLDCPSDILVDVINASI 229
            ....| :..|....:|....  |..||     .|.|.:|  .||...|.::....:.|..|...|
plant   180 FMPFL-FDALQDVEVKRSVIPPEAIDDEIQKELRKLMER--QARVFVVHMESSLALRVFQIARDI 241

  Fly   230 G-------YNMTGSFNHLFLTNLDTHLSGIDGFYSRDFTVAVAAVRIRTYVP------------- 274
            |       :.||....|:.     .|::.     .|........:.:|::||
plant   242 GMMEEGYVWLMTNGMTHMM-----RHINN-----GRSLNTIEGVLGVRSHVPKSKELGDFRLRWK 296

  Fly   275 -------PPVHDEIDVFDNSVDTRFSSLGSQLVYDSIVLFYNALLEISQRPGFYIPNFSCGR--- 329
                   |.:.|:::||            :...||||.....|:.:.:.:..:|....:..:
plant   297 RTFEKENPSMRDDLNVF------------ALWAYDSITALAKAVEKANTKSLWYDNGSTLSKNRT 349

  Fly   330 -----GFWQPGPRLVEQMKQITPKMVKPPFKTQRLQINADGQREDFNLEVYNPI--IDRVTHIWN 387
                 |....||.|.:...::....:...||.      .|||.:....|:.|.:  .:|:...|.
plant   350 DLGNVGVSLYGPSLQKAFSEVRFNGLAGEFKL------IDGQLQSPKFEIINFVGNEERIIGFWT 408

  Fly   388 KEFQLVDFEKLRENSTQAL----KQKRLQNKEDFSQKPIRYTVATRVGKPYFSW----------R 438
            ....|:|.....:.:...:    |.|.:....:...|.:|..|..:.|  :|.:          :
plant   409 PRDGLMDATSSNKKTLGPVIWPGKSKIVPKGWEIPGKKLRVGVPMKKG--FFDFVKVTINPITNK 471

  Fly   439 EEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYGSYDANTDEWDGIIRQLIDNNA 503
            :.|.|.   ..|.||....:|.|::..|              |.|:: :.:.::.::.|:.|...
plant   472 KTPTGY---AIEIFEAALKELPYLVIPE--------------YVSFE-SPNNYNNLVYQVYDKTW 518

  Fly   504 QIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPPPKADIYAFLNPYNAEVWL-----FVMIA 563
            ...:.|:|||..|....|||:||.:.|:|::.........|.:.||.|::.|:|:     ||.|.
plant   519 DAVVGDITITANRSLYADFTLPFTESGVSMMVPVRDNENKDTWVFLEPWSLELWVTTGCFFVFIG 583

  Fly   564 MMITAFALIFTGRIDQYEWDQPVENVNREMERQNIWHLSNALWLVLGSMLNQGCDLLPRGLPMRL 628
            .::..|.                ..||.:......:.:..:||....:|:....:.:...| .|.
plant   584 FVVWLFE----------------HRVNTDFRGPPQYQIGTSLWFSFSTMVFAHRENVVSNL-ARF 631

  Fly   629 LTAFWWIFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQNKVQFGTIRGGA------TSVYF 687
            :...|....|:::|:|.|.|.:|:|...:...:.:::||: :|:...| .:|||      ..:.|
plant   632 VVVVWCFVVLVLTQSYTASLTSFLTVQSLQPTVTNVNDLI-KNRDCVG-YQGGAFVKDILLGLGF 694

  Fly   688 SESNDTDNRMAWNKMLSFKPDAFTKNNEEGVDRVKLSKGTYAFLMETTNLQYYVQRNC-ELTQIG 751
            .|.             ..||....|:.::.:.:.| |||..|...|...|:..:.::| :...:.
plant   695 HED-------------QLKPFDSAKDADDLLSKGK-SKGIAAAFDEVAYLKAILSQSCSKYVMVE 745

  Fly   752 ESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNKWFNSNESTCDSNVPTIDDGQFDMD 816
            .:|....:|.|.|.|:......|..||.|::.....::.::|| ..::.|...:..:...:.::.
plant   746 PTFKTGGFGFAFPKNSPLTGEFSRAILNLTQNNVTQQIEDRWF-PKKNDCPDPMTALSSNRLNLS 809

  Fly   817 SVGGLFVVLIVGVVVGLVIGVAEFLWHVQRISVKEKIPPMLALKAEFYFVIRFWLTRKPL--HTY 879
            |..|||::....:...|::.||.||:. .|.::.:.....|..|.:|.|.|   ...|.:  ||:
plant   810 SFLGLFLIAGTAISFSLLVFVALFLYE-HRHTLGDDSEDSLWRKLKFLFKI---FDEKDMNSHTF 870

  Fly   880 RQSR-------DSTSTGYSSLEQIT---SASSAKKKKKTRRI 911
            :.|.       .:..|...|..|||   .:.|..::.:.||:
plant   871 KNSAIHNISSPMTHKTPSPSTVQITPWPQSPSQNREFELRRV 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	84/435 (19%)
		ANF_receptor	41..378	CDD:279440	79/403 (20%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	83/394 (21%)
		Lig_chan	555..822	CDD:278489	55/278 (20%)
GLR2.9	NP_001325277.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I1813
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.920