Protein Alignment GluRIIB and GLR2.3

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001325281.1
• Gene: GLR2.3 / 817007
• AraportID: AT2G24710
• Length: 919
• Species: Arabidopsis thaliana
• Alignment Length: 966
• Identity: 196/966 - (20%)
• Similarity: 353/966 - (36%)
• Gaps: 247/966 - (25%)

  Fly     4 LQFLVLL----ALAIASGANEDTLVIKIGAIF-FDT----------EMKLADAFSAALEEVNAIN 53
            |.|.:||    .|....|.|....::.:|.:. .||          .|.::|.:|:        |
plant    30 LFFCILLVFFFCLEFNRGQNNGKTLVDVGVVTDVDTSHSKVVMLCINMSISDFYSS--------N 86

  Fly    54 PALKLDAIKRYVTVDDSIVLQDISCDLIGSGVA-----------AIFGPSSKTNSDIVEVLCNMT 107
            |..:...:   |.|.||      ..|::|:.:|           ||.||.:...:..:..:...:
plant    87 PQFETRLV---VNVGDS------KSDVVGAAIAALDLIKNKQVKAILGPWTSMQAHFLIEIGQKS 142

  Fly   108 GIPHLQFDWHPQQSNRERMNHQLTVNVAPMELFLSAAFSDILASKTFDWKSFTIAYERSSHLIRL 172
            .:|.:.:                            :|.|.||.|.            ||.:.:|.
plant   143 RVPIVSY----------------------------SATSPILTSL------------RSPYFLRA 167

  Fly   173 QHILAWK-QLHKAGIKMQEFERGDDYRILWKRI------NNAREKFV--LLDCPSDILVDV-INA 227
            .:..::: |..||.||:          ..|:.:      |...|..:  |.|...||.|.: ..:
plant   168 TYEDSFQVQPIKAIIKL----------FGWREVVPVYIDNTFGEGIMPRLTDALQDINVRIPYRS 222

  Fly   228 SIGYNMTG---SFNHLFLTNLDTHLSGIDGFY---SRDF-------------------------- 260
            .|..|.|.   |...|.:.|:.|.:..:..:|   ||.|
plant   223 VIAINATDHEISVELLKMMNMPTRVFLVHMYYDLASRFFIKAKELGLMEPGYVWILTNGVIDDLS 287

  Fly   261 ---TVAVAAVR----IRTYVPPPVHDEIDVFDNSVDTRFSSLGSQL--------VYDSIVLFYNA 310
               ..||.|:.    |:||:|.  ..:::.|    .:|:.||..::        .||:......|
plant   288 LINETAVEAMEGVLGIKTYIPK--SPDLEKF----RSRWRSLFPRVELSVYGLWAYDATTALAVA 346

  Fly   311 LLEISQRPGFYIPNFSCGR--------GFWQPGPRLVEQMKQITPKMVKPPFKTQRLQINADGQR 367
            :.|.......:......||        |..|.||:|::.:..:..:.:...|:..|      ||.
plant   347 IEEAGTNNMTFSKVVDTGRNVSELEALGLSQFGPKLLQTLLTVQFRGLAGEFRFFR------GQL 405

  Fly   368 EDFNLEVYNPII--DRVTHIWNKEFQLVDFEKLRENSTQALKQ-----KRLQNKEDFSQKPIRYT 425
            :....|:.|.|.  ::....|.:...||.....:.:|..||..     |.:....:....|..:.
plant   406 QPSVFEIVNIINTGEKSIGFWKEGNGLVKKLDQQASSISALSTWKDHLKHIVWPGEADSVPKGWQ 470

  Fly   426 VAT-----RVGKPYFSWREEPEGVHYE---GNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYG 482
            :.|     |:|.|..:...:...|..:   .:....|:.:|....:.:|..:|.::|.:...|..
plant   471 IPTKGKKLRIGVPKRTGYTDLVKVTRDPITNSTVVTGFCIDFFEAVIRELPYDVSYEFIPFEKPD 535

  Fly   483 SYDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPPPKADIYA 547
            ...|.  .::.::.|:........:.|.||...|.|.||||.||::.|:.::.....|.|.|...
plant   536 GKTAG--NYNDLVYQVYLGRYDAVVGDTTILVNRSSYVDFTFPFIKSGVGLIVEMTDPVKRDYIL 598

  Fly   548 FLNPYNAEVWLFVMIAMMI---TAFALIFTGRIDQYEWDQPVENVNREMERQNIWHLSNALWLVL 609
            |:.|.:.::||...|:..:   |.:.|       :|:.:.......|       :..|...|...
plant   599 FMKPLSWKLWLTSFISFFLVGCTVWVL-------EYKRNPDFSGPPR-------FQASTICWFAF 649

  Fly   610 GSMLNQGCDLLPR----GLPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQ 670
            .:|:     ..||    ....|.|...|:...|:::|:|.|.||:.:||.|:...|.|:..|:::
plant   650 STMV-----FAPRERVFSFWARALVIAWYFLVLVLTQSYTASLASLLTSQKLNPTITSMSSLLEK 709

  Fly   671 NKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTKNNEEGVDRVKLSKG------TYA 729
            .:    |:....||....:..  :.....:.::.|       :..|..|.: ||||      :.|
plant   710 GE----TVGYQRTSFILGKLK--ERGFPQSSLVPF-------DTAEECDEL-LSKGPKKGGVSGA 760

  Fly   730 FLMETTNLQYYVQRNCE-LTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNKW 793
            || |...|:.::.:.|. ...:.|.|....:|...|:.:...:::|..||:::|..:..:|...|
plant   761 FL-EIPYLRLFLGQFCNTYKMVEEPFNVDGFGFVFPIGSPLVADVSRAILKVAESPKAMELERAW 824

  Fly   794 FNSNESTC-------DSNVPTIDDGQFDMDSVGGLFVVLIVGVVVGLVIGVAEFLW 842
            |...|.:|       |.| |:....|.|:||    |:.|.|||::..|:.:..|.:
plant   825 FKKKEQSCPDPITNPDPN-PSFTSRQLDIDS----FLFLFVGVLLVCVMALGNFTY 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	82/455 (18%)
		ANF_receptor	41..378	CDD:279440	75/412 (18%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	83/394 (21%)
		Lig_chan	555..822	CDD:278489	63/287 (22%)
GLR2.3	NP_001325281.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I1813
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.920