Protein Alignment GluRIIB and Ir7e

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 868
• Identity: 154/868 - (17%)
• Similarity: 264/868 - (30%)
• Gaps: 360/868 - (41%)

  Fly    47 EEVNAINPALK---LDAIKRYV-TVDDSIVL-----QDISCDLIGSGVAAIFGPSSKTNSDIVEV 102
            |::|.||..:.   |..:..|: :|..|:||     .:.:|:.....::.:|.........||.|
  Fly    16 EQMNHINEFVARAVLHVVHHYILSVTPSLVLTLCCRSNHTCNFYNKMMSTLFREWGLAPLQIVNV 80

  Fly   103 LCNMTGIPHLQFDWHPQQSNRERMNHQLTVNVAPMELFLSAAFSDILASKTFDWKSFTIAYERSS 167
            |   .|:|     |||....|.                .:..|:|..|           |:|.
  Fly    81 L---RGVP-----WHPVPGRRH----------------FNVIFTDSFA-----------AFEE-- 108

  Fly   168 HLIRLQHILAWKQLHKAGIKMQEFERGDDYRILWKRINNAREKFVLLDCPSDILVDVINASIGYN 232
                              |:|:.:.|..:|.         ...|:.|.....:|
  Fly   109 ------------------IRMEYYSREYNYN---------EHYFIFLQARDRLL----------- 135

  Fly   233 MTGSFNHLFLTNLDTHLSGIDGFYSRDFTVAVAAVRIRTYVPPPVHDEIDVFDNSVDTRFSSLGS 297
             .|....:|                 |:     ..|.|.     :|..|.|..::.|
  Fly   136 -QGEMRLIF-----------------DY-----CWRYRL-----IHCSIQVQKSNGD-------- 164

  Fly   298 QLVYDSIVLFYNALLEISQRPGFYIPNFSCGRGFWQP-------GPRLVEQMKQITPKMVK---- 351
                   :|||:           |.|....|....:|       |..|||  ..:.|:.::
  Fly   165 -------ILFYS-----------YYPFGEHGCSDMEPQLINRYNGSMLVE--PDLFPRKLRNFFG 209

  Fly   352 ----------PPFKTQRLQINADGQREDFNLEVYNPIIDRVTHIWNKEFQLVDFEKLRENS---- 402
                      |||.|      .|..:|                           |.||.|.
  Fly   210 CPLRCALWDVPPFLT------LDEDQE---------------------------EVLRVNGGYEG 241

  Fly   403 --TQALKQKRLQNKEDFSQKPIRYTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQ 465
              ..||.:|            :.:|:|.|  |.:.:.|:|               |::::
  Fly   242 RLLLALAEK------------MNFTIAVR--KVHVNMRDE---------------ALEML----- 272

  Fly   466 ECKFDFNFEPVRDNKYGSYDANTDEWD---GIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFM 527
                                 ..||.|   |.|||               |.||..|...:..:.
  Fly   273 ---------------------RRDEVDLTLGGIRQ---------------TVARGMVATSSHNYH 301

  Fly   528 Q----LGISILSYKEPPPKADIYAFLNPYNAEVWLFVMIAMMITAFALIFTGRIDQYEWDQPVEN 588
            |    .|:...||:  ....||..:  ||..::|:.::..:.::|...:..||
  Fly   302 QTREVFGVLASSYE--LSSFDILFY--PYRLQIWMGILGVVALSALIQLIVGR------------ 350

  Fly   589 VNREMERQNIWHLSNALWLVLGSMLNQGCDLL--PRGLPMRLLTAFWWIFALLISQTYIAKLAAF 651
                |.|:   .:.:..||.| .::..|..||  ||....||......::.|:|...|...|...
  Fly   351 ----MLRE---RMGSRFWLNL-ELVFVGMPLLECPRSHTARLYCVMLMMYTLIIRTIYQGLLYHL 407

  Fly   652 ITSSKIAGDIGSLHDLVDQN--------------------KVQFGTIRGGA--TSVYFSESNDTD 694
            |.:.::.....::..||.:|                    .::|..:...:  ..:||.|:|...
  Fly   408 IRTHQLNRWPQTIESLVQKNFTVVLTPIVQEVLDEIPSVQHMRFRLLEANSELDPLYFLEANHQL 472

  Fly   695 NRMAWNKMLSFKPDAFTKNNEEGVDRV----KLSKGTYAFLMETTNLQYYVQRNCELTQIGESFG 755
            .:......|    |.|...|....|:|    :...|.:..::....:      :.:||.    :.
  Fly   473 RQHVTASAL----DIFIHFNRLSADKVHQRGEQGSGAHFEIVPEDII------SMQLTM----YL 523

  Fly   756 EKHYGIAVPLNADFRSNLSVGILRLSERGELFK--LRNKWFNSNESTCDSNVPTIDDGQFDMDSV 818
            .||..:...||.:.....|||:|.:..|.||.:  |||:.......|.:               :
  Fly   524 AKHSFLIDQLNEEIMWMRSVGLLSVWSRWELSESYLRNEQSFQVLGTME---------------L 573

  Fly   819 GGLFVVLIVGVVVGLVIGVAEFL 841
            ..:|::::||::|||::.:.|.:
  Fly   574 YAIFLMVLVGLIVGLLVFILELV 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	61/375 (16%)
		ANF_receptor	41..378	CDD:279440	61/360 (17%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	78/409 (19%)
		Lig_chan	555..822	CDD:278489	53/296 (18%)
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	33/197 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462640
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740