Protein Alignment GluRIIB and Ir76a

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Alignment Length: 714
• Identity: 123/714 - (17%)
• Similarity: 238/714 - (33%)
• Gaps: 207/714 - (28%)

  Fly   246 DTHLSGIDGFYSRDFTVAVAAVRIRTYVPPPV----------HDEIDVFDNSV-DTRFSSLGSQL 299
            |:|.:.|....:.||       |:.|..|.|:          ..:.||:|..: :..|.  |..:
  Fly    25 DSHATCIFWHPAFDF-------RLETVHPMPLIIMDWHRWANRSDQDVYDYKIKEDEFE--GKGI 80

  Fly   300 VYDSIVLFYNALLEISQRPGF-----YIPNFSCGRGFWQPGPRLVEQMKQITPKMVKPPFKTQRL 359
            .|:...|.....:|.|....|     .||.|:
  Fly    81 PYNDWTLRLTVAIERSHCETFIAFQEQIPEFA--------------------------------- 112

  Fly   360 QINADGQREDFNLEVYN---PIIDRVTHIWNKEFQ------------------LVDFEKLRENST 403
                   |..::..:|:   .:.:|...::.|||:                  ||...:...:||
  Fly   113 -------RYFYHASIYSIWRSLRNRFMFVYTKEFEDKKDSYLSGYIFQDQPNILVITSQYLNSST 170

  Fly   404 QALKQKRLQNKEDFSQ--KPIRYTVATR-----------------------------VG----KP 433
            ..:|..|.....:|::  :|:.:.:..|                             :|    ||
  Fly   171 FEIKTNRFVGPRNFNKNPEPVEFYILQRFDAKGTKATWETQSAMSSKMRNLKGREVVIGIFDYKP 235

  Fly   434 YFSWREEPEGVHYEGNERF--------EGYAVDLIYMLAQECKFDFNFEPVRDNKYGSYDANTDE 490
            :.....|...::|   :||        :|..:.|:.:..:........:......:|....|...
  Fly   236 FMLLDYEKPPLYY---DRFMNTTDVTIDGTDIQLMLIFCELYNCTIQVDTSEPYDWGDIYLNASG 297

  Fly   491 WDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPPPKADI--YAFLNPYN 553
            : |::..::|.....|:..:.:.......:|.|....:.|::.|   .|.|...|  ...|.|:.
  Fly   298 Y-GLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCL---VPAPNRLISWTLLLRPFQ 358

  Fly   554 AEVWLFVMIAMMITAFALIFTGRIDQYEWDQPVENVNREMERQNIWHLSNALWLV--LGSMLNQG 616
            ..:|:.||:.:::.:.||..|.|     |:      :..:...|.|..|.....:  |...:||.
  Fly   359 FVLWMCVMLCLLLESLALGITRR-----WE------HSSVAAGNSWISSLRFGCISTLKLFVNQS 412

  Fly   617 CDLLPRGLPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQNKVQFGTIRGG 681
            .:.:.....:|.:....::..::::..|...|||.:|...:.....|...|.|...:..||.:..
  Fly   413 TNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEEAADSRQRLFDHKLIWTGTSQAW 477

  Fly   682 ATSVYFSESNDTDNRMAWNKMLSFKP----------DAFTKNNEEG--VDRVKLSKGTYAFLMET 734
            .|::        |.|.|...:|....          .||:...:.|  |:|::     :..|..|
  Fly   478 ITTI--------DERSADPVLLGLMEHYRVYDANLISAFSHTEQMGFVVERLQ-----FGHLGNT 529

  Fly   735 TNLQYYVQRNCELTQIGESFGEKHYGIAVP--------LNA--DFRSNLSVGILRLSERG-ELF- 787
            ..::     |..|.::.....:.::...|.        |||  ||       ||.....| :.|
  Fly   530 ELIE-----NDALKRLKLMVDDIYFAFTVAFVPRLWPHLNAYNDF-------ILAWHSSGFDKFW 582

  Fly   788 --KLRNKWFNSNEST--CDSNVPTIDDG--QFDMDSVGGLFVVLIVGVVVGLVIGVAEFLWHVQ 845
              |:..::.|::...  ..|....:|.|  :..:|:..||.::...|::..|:..:.| ||..|
  Fly   583 EWKIAAEYMNAHRQNRIVASEKTNLDIGPVKLGIDNFIGLILLWCFGMICSLLTFLGE-LWRGQ 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	28/183 (15%)
		ANF_receptor	41..378	CDD:279440	24/150 (16%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	74/443 (17%)
		Lig_chan	555..822	CDD:278489	56/298 (19%)
Ir76a	NP_001097647.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462637
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840