Protein Alignment GluRIIB and Ir75c

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 119/546 - (21%)
• Similarity: 214/546 - (39%)
• Gaps: 114/546 - (20%)

  Fly   354 FKTQRLQINAD---GQREDFNLEVYNPIIDRVTHIWNKEFQLVDFE--------KLRENSTQALK 407
            |:...|.:|||   ..|||....:.:.:.::.:|:..|....||..        :::|..::...
  Fly   119 FEGANLSLNADVTYVSREDEERFILHDVYNKGSHLGGKLNITVDQTLQCNRSHCQVKEYLSELHL 183

  Fly   408 QKRLQNKEDFSQKPIRYTVATRVGKPYFSWREE------------PEGVHYEGN------ERFEG 454
            :.|||::.|.|....|......| .|..|..||            .:.:...||      :...|
  Fly   184 RPRLQHRMDLSSVTFRLAALVSV-LPINSSEEELLEFLNSDRDSHMDSISRIGNRLIMHTQEILG 247

  Fly   455 YAVDLIYMLAQECKFDFNFEPVRDNKYGSYDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSV 519
            :.:..|:     |              |::... |.:.|.|..|.:.:|:  :|
  Fly   248 FKLHYIW-----C--------------GTWSVQ-DAFGGAIGMLTNESAE--LC----------- 279

  Fly   520 VDFTVPFMQLGISILSYKEP---------------PPKADIYA--FLNPYNAEVWLFVMIAMMIT 567
               |.||:. ..:.|.|..|               |..|.|.|  ||.|:...|| |....::|.
  Fly   280 ---TTPFVP-SWNRLHYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVW-FAFAGLLIF 339

  Fly   568 AFALIFTGRIDQYEWDQPVENVNREMER--QNIWHLSNALWLVLGSMLNQGCDLLPRGLPMRLLT 630
            |..|::.....:..|          |:|  ..|..|.::..:..|:...||..|:|:....||..
  Fly   340 AGVLLWMIFHLERHW----------MQRCLDFIPSLLSSCLISFGAACIQGSYLMPKSAGGRLAF 394

  Fly   631 AFWWIFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQN-KVQFGTIRGGATSVYFSESNDTD 694
            ....:.:.|:...|.:.:.:.:..|.:..:|.::..|.|.: .|.|.|:  ..|..|...|...|
  Fly   395 IAVMLTSFLMYNYYTSIVVSTLLGSPVRSNIRTIQQLADSSLDVGFDTV--PFTKTYLVSSPRPD 457

  Fly   695 NRMAWNKMLSFK--PDAFTKNNEEGVDRVKLSKGTYAFLMETTNLQYYVQRNC---ELTQIGESF 754
            .|..:.:.:..|  |::...:.||||.||:...| :.:..|.:.:.::|:::.   |::.:.|..
  Fly   458 IRSLYKQKVESKRDPNSVWLSPEEGVIRVRDQPG-FVYTSEASFMYHFVEKHYLPREISDLNEII 521

  Fly   755 GEKH---YGIAVPLNADFRSNLSVGILRLSERGELFKLRNKWFNSNESTCDSNVPTIDDGQFDMD 816
            ....   ||: |.||:.:|..|:...:|:.|.|...| ::::|:..:....||...|   |..|:
  Fly   522 LRPESAVYGM-VHLNSTYRQLLTQLQVRMLETGITSK-QSRFFSKTKLHTFSNSFVI---QVGME 581

  Fly   817 SVGGLFVVLIVGVVVGLVIGVAEFLW 842
            ....||:.|:|...:.|:|.:.|..|
  Fly   582 YAAPLFISLLVAYFLALLILILEICW 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	10/41 (24%)
		ANF_receptor	41..378	CDD:279440	8/26 (31%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	87/418 (21%)
		Lig_chan	555..822	CDD:278489	62/277 (22%)
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	54/239 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462583
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840