Protein Alignment GluRIIB and Ir60a

DIOPT Version :10

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Alignment Length: 735
• Identity: 137/735 - (18%)
• Similarity: 237/735 - (32%)
• Gaps: 182/735 - (24%)

  Fly   204 INNAREKFVLLDCP-SDILVDVINASIG---------------YNMTGSFN----HLFLTNLDTH 248
            ::|.....|:...| .|:..||..|.:|               ...|.::|    |.|      |
  Fly    27 LSNETANTVIFMLPEKDLGPDVWKAGVGCLDSFAQIFFFRNPKERFTRAYNLMLVHAF------H 85

  Fly   249 LSG----IDGFYSRDFTVAVAAVRIRTYVPPPVHDEI----DVFDNSVDTRFSSLGSQLVYDSIV 305
            ||.    |...:|:....||      |...||..:|:    ...|.::.......|..::.|:.|
  Fly    86 LSSPADQIQEGFSKLINEAV------TNPGPPDREELFQMRVASDYNITNGTEDKGELILADNYV 144

  Fly   306 LFYNA---LLEISQRPGFYIPNFSCGRGFWQPGPRLVEQMKQIT----P--------KMVKPPFK 355
            :..::   |.|:.::....:.:       |.||.|.:......|    |        |.:...|.
  Fly   145 IVVDSVDRLKELMKKKIVEMRS-------WNPGARFLVLFHNATCRNRPLGVASNIFKDLMEMFY 202

  Fly   356 TQRLQINADGQREDFNL---EVYNPIIDRVTHIWNKEFQLVDFEKLRENSTQALKQKRLQNKEDF 417
            ..|:.:.......::||   :.|:.:..|:.:: ....|..| .||..|:. .:|.........|
  Fly   203 VHRVALLYANSTMNYNLLVNDYYSNVNCRILNV-QSVGQCHD-GKLYPNNA-VVKASMQDYVSGF 264

  Fly   418 SQKPIRYTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYG 482
            |.:...:...:.:..|:..            .:...|..:.::..:....|||.|.....::: |
  Fly   265 SPRNCTFFACSSISAPFVE------------ADCILGLEMRILGFMKNRLKFDVNQTCSLESR-G 316

  Fly   483 SYDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPPPKADIYA 547
            ..|...: |.|::.::.:|.     ||....                     .|......||.:.
  Fly   317 EMDGPAN-WTGLLGKVQNNE-----CDFVFG---------------------GYYPDNEVADHFW 354

  Fly   548 FLNPY--NAEVWLFVMIAMMITAFALIFTGRIDQYEWDQPVENVNREMERQNIWHLSNALWLVLG 610
            ..:.|  :|..|...|........||:  |..:.|.|...:          .|..:|...|..|.
  Fly   355 GSDTYLQDAHTWYIKMADRRPAWQALV--GIFEAYTWIGFI----------LILIISWLFWFTLV 407

  Fly   611 SMLNQGCDLLPRGLPMRLLTAFWWIFALLIS---------------------QTYIAKLAAFITS 654
            .:|.:     |:......|||   |.||.::                     ..|...:.|..||
  Fly   408 MILPE-----PKYYQQLSLTA---INALAVTISIAVQERPICETTRLFFMALTLYGLNVVATYTS 464

  Fly   655 SKIA--GDIGSLHDLVDQNKVQFGTIRGGATSVYFSESND---TDNRM----AWNKMLSFKPDAF 710
            ..||  .|.|.||.|.:..:|....|..|.    ..||.|   .|:.|    .:|....|.|.:
  Fly   465 KMIATFQDPGYLHQLDELTEVVAAGIPFGG----HEESRDWFENDDDMWIFNGYNISPEFIPQS- 524

  Fly   711 TKNNEEGV---DRVKLSKGTYAFLMETTNLQYYVQRNCELTQIGESFGEKHYGIAVPLNADFRSN 772
              .|.|.|   .|..||...|.......::.|....|...:.: :...:..:.....:|:..|..
  Fly   525 --KNLEAVKWGQRCILSNRMYTMQSPLADVIYAFPNNVFSSPV-QMIMKAGFPFLFEMNSIIRLM 586

  Fly   773 LSVGILRLSERGELFKLRNKWFNSNESTCDSNVPTIDDGQFDM--DSVGGLFVVLIVGVVVGLVI 835
            ..|||.:..:..  |:..|.:.|    ..:...|...:....:  :.:.|.|.:|:||.....:.
  Fly   587 RDVGIFQKIDAD--FRYNNTYLN----RINKMRPQFPETAIVLTTEHLKGPFFILVVGSCWAALT 645

  Fly   836 GVAEFL---WHVQRISVKEK 852
            .:.|.:   |..|.:|..|:
  Fly   646 FIGELIIHRWRTQLVSTSEQ 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..387	CDD:380605	42/228 (18%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	75/407 (18%)
Ir60a	NP_611901.1	None