Protein Alignment GluRIIB and Ir40a

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Alignment Length: 748
• Identity: 143/748 - (19%)
• Similarity: 250/748 - (33%)
• Gaps: 217/748 - (29%)

  Fly   208 REKFVLLDCPSDILVDVINA---SIGYNMTGSFNHLFLTNLDTHLSGIDGFYSRDFTVAVAAVRI 269
            :|:.|.||   |.|..:..:   |:.::.|    .||..:::.:|.|.:...|.
  Fly    65 KERNVYLD---DFLQRLHRSNYKSVVFSQT----ELFFQHIEENLQGANECISL----------- 111

  Fly   270 RTYVPPPVHDEIDVFDNSVDTRFSSLGSQLVYDSIVLFYNALLEISQRPGFYIPNFSCGRGFWQP 334
                   :.||.:...||:..|  .||.:|   |:.:||                   ....|.|
  Fly   112 -------ILDEPNQLLNSLHDR--HLGHRL---SLFIFY-------------------WGARWPP 145

  Fly   335 GPRLV---EQMKQITPKMVKPPFKTQRLQINADGQREDFNLEVYNPIIDRVTHIW----NKEFQL 392
            ..|::   |.::.:.  :.:|..|..|:..|......|..|::.|         |    |...|.
  Fly   146 SSRVIRFREPLRVVV--VTRPRKKAFRIYYNQARPCSDSQLQLVN---------WYDGDNLGLQR 199

  Fly   393 VDFEKLRENSTQALKQKRLQNKEDFSQKPIRYTVATRVGKPYF-------SWREEPEGVHYEGNE 450
            :           .|....|....:|..:..|..|..  ..|:|       |:.|:.|....:..|
  Fly   200 I-----------PLLPTALSVYANFKGRTFRVPVFH--SPPWFWVTYCNNSFEEDEEFNSLDSIE 251

  Fly   451 RFE-----GYAVDLIYMLAQECKFDFNFEPVRDNKYGSY------DANTDEWDGIIRQLIDNNAQ 504
            :.:     |....|:.:|::...|.|.:........||.      |:| |.:.|.|..|....|.
  Fly   252 KRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRTQGSMRSEDGKDSN-DSFTGGIGLLQSGQAD 315

  Fly   505 IGICDLTITQARRSVVDFTVPFMQLGIS-ILSYKEPPPKADIYAFLNPYNAEVWLFVMIAMMITA 568
            ..:.|:.::..||..::|:  |..|..| ..:...|....:..|.:.|:..::|..:::.::.:
  Fly   316 FFLGDVGLSWERRKAIEFS--FFTLADSGAFATHAPRRLNEALAIMRPFKQDIWPHLILTIIFS- 377

  Fly   569 FALIFTGRID-QYEWDQPVENVNREMERQNIWHL------------------------------- 601
             ..||.|.|. .|.|       .|.....::.||
  Fly   378 -GPIFYGIIALPYIW-------RRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQM 434

  Fly   602 -----SNALWLVLGSMLNQGCDLLPRGLPMRLLTAFWWIFA-LLISQTYIAKLAAFITSSKIAGD 660
                 ...:|..|...|.|.|:.|..|...:.||..:||.| .:::..|.|:|.:..........
  Fly   435 PHQLFQKCIWFTLRLFLKQSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPP 499

  Fly   661 IGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFK-------------PDAFTK 712
            |.:|      .::|...|..|.......||:..:  |..|....|:             |..|..
  Fly   500 INTL------QRLQAAMIHDGYRLYVEKESSSLE--MLENGTELFRQLYALMRQQVINDPQGFFI 556

  Fly   713 NN---------EEGVDRVKLSKGTYAFLMETTNLQYYVQRNCELTQIGESFGEKHYGIAVPLNAD 768
            ::         |.|.|:..|......|.    |:|.|...|.:|:|   ....::..:||.:...
  Fly   557 DSVEAGIKLIAEGGEDKAVLGGRETLFF----NVQQYGSNNFQLSQ---KLYTRYSAVAVQIGCP 614

  Fly   769 FRSNLSVGILRLSERGELFKL------------------------RNKWFNSNESTCDSNVPTID 809
            |..:|:..:::|.|.|.|.|:                        :|....|...:.||.|.:
  Fly   615 FLGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVIS-- 677

  Fly   810 DGQFDMDSVGGLFVVLIVGVVVGLVIGVAEFLW 842
              ..::..:.|.|:.|.||.:...||.:.|.::
  Fly   678 --PLNLRMLQGAFIALGVGSLAAGVILLLEIVF 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	38/194 (20%)
		ANF_receptor	41..378	CDD:279440	35/175 (20%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	90/475 (19%)
		Lig_chan	555..822	CDD:278489	63/350 (18%)
Ir40a	NP_610140.4	PBP2_LTTR_substrate	216..338	CDD:330233	27/126 (21%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:328725	23/98 (23%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:328725	32/155 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462627
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840